Mouse Anti-GDI1 Recombinant Antibody (CBFYH-0314) (V2LY-1225-LY1026)

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Basic Information

Host Animal
Mouse
Clone
CBFYH-0314
Application
WB, IHC
Immunogen
Full length human recombinant protein of human GDI1.
Host Species
Mouse
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
ApplicationNote
WB1:20-1:50
IHC1:500-1:2,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, BSA, glycerol
Preservative
Sodium azide
Concentration
1 mg/ml
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
GDP Dissociation Inhibitor 1
Entrez Gene ID
Human2664
Mouse14567
Rat25183
UniProt ID
HumanP31150
MouseP50396
RatP50398
Function
Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes.
Biological Process
Negative regulation of axonogenesis Source: UniProtKB
Negative regulation of protein targeting to membrane Source: UniProtKB
Positive regulation of axon extension Source: Ensembl
Protein transport Source: InterPro
Rab protein signal transduction Source: UniProtKB
Response to calcium ion Source: Ensembl
Signal transduction Source: ProtInc
Vesicle-mediated transport Source: GO_Central
Cellular Location
Cytoplasm; Trans-Golgi network
Involvement in disease
Mental retardation, X-linked 41 (MRX41):
A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. Intellectual deficiency is the only primary symptom of non-syndromic X-linked mental retardation, while syndromic mental retardation presents with associated physical, neurological and/or psychiatric manifestations.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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