Mouse Anti-HTN1 (AA 20-57) Recombinant Antibody (CBFYH-2488) (CBMAB-H3503-FY)

Name: Mouse Anti-HTN1 (AA 20-57) Recombinant Antibody (CBFYH-2488)
SKU: CBMAB-H3503-FY
Rating: 5 (1 reviews)

See all HTN1 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBFYH-2488

Application

ELISA, WB

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.4, 50% glycerol

Preservative

0.02% Sodium azide

Concentration

0.2 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Epitope

AA 20-57

More Infomation

Target

Full Name

Histatin 1

Introduction

This gene encodes a member of the histatin family of small, histidine-rich, cationic proteins. They function as antimicrobial peptides and are important components of the innate immune system. Histatins are found in saliva and exhibit antibacterial, antifungal activities and function in wound healing.

Entrez Gene ID

3346

UniProt ID

P15515

Alternative Names

Histatin 1; Histidine-Rich Protein 1; Post-PB Protein; HIS1; PPB; Histatin-1

Function

Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities.

Biological Process

Antimicrobial humoral immune response mediated by antimicrobial peptide Source: UniProtKB
Biomineral tissue development Source: UniProtKB-KW
Defense response to bacterium Source: UniProtKB
Defense response to fungus Source: UniProtKB-KW
Killing of cells of other organism Source: UniProtKB

Cellular Location

Secreted

PTM

Depending on the authors, the form called histatin-2 is alternatively a proteolytic product, or the non-phosphorylated form of histatin-1.

Ma, D., Sun, W., Fu, C., Nazmi, K., Veerman, E. C., Jaspers, R. T., ... & Wu, G. (2022). GPCR/endocytosis/ERK signaling/S2R is involved in the regulation of the internalization, mitochondria-targeting and-activating properties of human salivary histatin 1. International Journal of Oral Science, 14(1), 42.

Son, K. N., Lee, H., Shah, D., Kalmodia, S., Miller, R. C., Ali, M., ... & Aakalu, V. K. (2021). Histatin‐1 is an endogenous ligand of the sigma‐2 receptor. The FEBS journal, 288(23), 6815-6827.

Dewi, N. K. A. F., Permatasari, N., & Sujuti, H. (2021). Effect of Histatin-1 Proteins to Fibroblasts Growth Factor-2 (FGF2) Concentrate and Fibroblasts Cell Migration on Human Gingival Fibroblast (HGF) Culture. Research Journal of Life Science, 8(2), 95-102.

Kalmodia, S., Son, K. N., Cao, D., Lee, B. S., Surenkhuu, B., Shah, D., ... & Aakalu, V. K. (2019). Presence of histatin-1 in human tears and association with aqueous deficient dry eye diagnosis: a preliminary study. Scientific reports, 9(1), 10304.

Huang, G. Q., Yi, G. G., Wu, L. W., Feng, S. F., Wu, W., Peng, L., ... & Lu, X. (2018). Protective effect of histatin 1 against ultraviolet‑induced damage to human corneal epithelial cells. Experimental and therapeutic medicine, 15(1), 679-684.

van Dijk, I. A., Veerman, E. C., Reits, E. A., Bolscher, J. G., & Stap, J. (2018). Salivary peptide histatin 1 mediated cell adhesion: a possible role in mesenchymal-epithelial transition and in pathologies. Biological chemistry, 399(12), 1409-1419.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-HTN1 (AA 20-57) Recombinant Antibody (CBFYH-2488)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-HTN1 Recombinant Antibody (CBFYH-2491) (CAT#: CBMAB-H3506-FY)

Mouse Anti-HTN1 (AA 20-57) Recombinant Antibody (CBFYH-2489) (CAT#: CBMAB-H3504-FY)

Mouse Anti-HTN1 Recombinant Antibody (CBFYH-2493) (CAT#: CBMAB-H3508-FY)

Mouse Anti-HTN1 Recombinant Antibody (CBFYH-2490) (CAT#: CBMAB-H3505-FY)

Mouse Anti-HTN1 Recombinant Antibody (A343) (CAT#: CBMAB-AP3036LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry