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HTN1

This gene encodes a member of the histatin family of small, histidine-rich, cationic proteins. They function as antimicrobial peptides and are important components of the innate immune system. Histatins are found in saliva and exhibit antibacterial, antifungal activities and function in wound healing. [provided by RefSeq, Aug 2014]

Full Name

Histatin 1

Function

Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities.

Biological Process

Antimicrobial humoral immune response mediated by antimicrobial peptide Source: UniProtKB
Biomineral tissue development Source: UniProtKB-KW
Defense response to bacterium Source: UniProtKB
Defense response to fungus Source: UniProtKB-KW
Killing of cells of other organism Source: UniProtKB

Cellular Location

Secreted

PTM

Depending on the authors, the form called histatin-2 is alternatively a proteolytic product, or the non-phosphorylated form of histatin-1.

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Anti-HTN1 antibodies

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Mouse Anti-HTN1 Recombinant Antibody (A343) (CBMAB-AP3036LY)

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Target: HTN1

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: A343

Application*: ICC, IHC, IP, WB

Mouse Anti-HTN1 Recombinant Antibody (CBFYH-2491) (CBMAB-H3506-FY)

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Target: HTN1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBFYH-2491

Application*: E

Mouse Anti-HTN1 Recombinant Antibody (CBFYH-2493) (CBMAB-H3508-FY)

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Target: HTN1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBFYH-2493

Application*: WB

Mouse Anti-HTN1 Recombinant Antibody (CBFYH-2490) (CBMAB-H3505-FY)

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Target: HTN1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBFYH-2490

Application*: IC, C, E, WB

Mouse Anti-HTN1 (AA 20-57) Recombinant Antibody (CBFYH-2489) (CBMAB-H3504-FY)

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Target: HTN1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBFYH-2489

Application*: E, IH, WB

Mouse Anti-HTN1 (AA 20-57) Recombinant Antibody (CBFYH-2488) (CBMAB-H3503-FY)

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Target: HTN1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBFYH-2488

Application*: E, WB

Human HTN1 ELISA Kit (V2LY-0626-LY4674)

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Target: HTN1

Sensitivity: 4.39 ng/mL

Detection Range: 10-2000 ng/mL

Sample Type: Serum, Plasma, cell culture supernates

Specificity: Human

Assay Type: Sandwich

Reactivity: Human

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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