HTN1

This gene encodes a member of the histatin family of small, histidine-rich, cationic proteins. They function as antimicrobial peptides and are important components of the innate immune system. Histatins are found in saliva and exhibit antibacterial, antifungal activities and function in wound healing. [provided by RefSeq, Aug 2014]

Full Name

Histatin 1

Function

Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities.

Biological Process

Antimicrobial humoral immune response mediated by antimicrobial peptide Source: UniProtKB
Biomineral tissue development Source: UniProtKB-KW
Defense response to bacterium Source: UniProtKB
Defense response to fungus Source: UniProtKB-KW
Killing of cells of other organism Source: UniProtKB

Cellular Location

Secreted

PTM

Depending on the authors, the form called histatin-2 is alternatively a proteolytic product, or the non-phosphorylated form of histatin-1.

Anti-HTN1 antibodies

Mouse Anti-HTN1 Recombinant Antibody (CBFYH-2493) (CBMAB-H3508-FY)

Datasheet

SDS

Target: HTN1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBFYH-2493

Application*: WB

Mouse Anti-HTN1 Recombinant Antibody (CBFYH-2491) (CBMAB-H3506-FY)

Datasheet

SDS

Target: HTN1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBFYH-2491

Application*: E

Mouse Anti-HTN1 Recombinant Antibody (CBFYH-2490) (CBMAB-H3505-FY)

Datasheet

SDS

Target: HTN1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBFYH-2490

Application*: IC, C, E, WB

Mouse Anti-HTN1 (AA 20-57) Recombinant Antibody (CBFYH-2489) (CBMAB-H3504-FY)

Datasheet

SDS

Target: HTN1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBFYH-2489

Application*: E, IH, WB

Mouse Anti-HTN1 (AA 20-57) Recombinant Antibody (CBFYH-2488) (CBMAB-H3503-FY)

Datasheet

SDS

Target: HTN1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBFYH-2488

Application*: E, WB

Mouse Anti-HTN1 Recombinant Antibody (A343) (CBMAB-AP3036LY)

Datasheet

SDS

Target: HTN1

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: A343

Application*: ICC, IHC, IP, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)