Human HTN1 ELISA Kit (V2LY-0626-LY4674)

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Tested Data
Request for COA
Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
4.39 ng/mL
Detection Range
10-2000 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
7.0 kDa
Components
  • Pre-coated ELISA Plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
Histatin 1
Function
Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities.
Biological Process
Antimicrobial humoral immune response mediated by antimicrobial peptide Source: UniProtKB
Biomineral tissue development Source: UniProtKB-KW
Defense response to bacterium Source: UniProtKB
Defense response to fungus Source: UniProtKB-KW
Killing of cells of other organism Source: UniProtKB
Cellular Location
Secreted
PTM
Depending on the authors, the form called histatin-2 is alternatively a proteolytic product, or the non-phosphorylated form of histatin-1.

Ma, D., Sun, W., Fu, C., Nazmi, K., Veerman, E. C., Jaspers, R. T., ... & Wu, G. (2022). GPCR/endocytosis/ERK signaling/S2R is involved in the regulation of the internalization, mitochondria-targeting and-activating properties of human salivary histatin 1. International Journal of Oral Science, 14(1), 42.

Son, K. N., Lee, H., Shah, D., Kalmodia, S., Miller, R. C., Ali, M., ... & Aakalu, V. K. (2021). Histatin‐1 is an endogenous ligand of the sigma‐2 receptor. The FEBS journal, 288(23), 6815-6827.

Dewi, N. K. A. F., Permatasari, N., & Sujuti, H. (2021). Effect of Histatin-1 Proteins to Fibroblasts Growth Factor-2 (FGF2) Concentrate and Fibroblasts Cell Migration on Human Gingival Fibroblast (HGF) Culture. Research Journal of Life Science, 8(2), 95-102.

Kalmodia, S., Son, K. N., Cao, D., Lee, B. S., Surenkhuu, B., Shah, D., ... & Aakalu, V. K. (2019). Presence of histatin-1 in human tears and association with aqueous deficient dry eye diagnosis: a preliminary study. Scientific reports, 9(1), 10304.

Huang, G. Q., Yi, G. G., Wu, L. W., Feng, S. F., Wu, W., Peng, L., ... & Lu, X. (2018). Protective effect of histatin 1 against ultraviolet‑induced damage to human corneal epithelial cells. Experimental and therapeutic medicine, 15(1), 679-684.

van Dijk, I. A., Veerman, E. C., Reits, E. A., Bolscher, J. G., & Stap, J. (2018). Salivary peptide histatin 1 mediated cell adhesion: a possible role in mesenchymal-epithelial transition and in pathologies. Biological chemistry, 399(12), 1409-1419.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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