Mouse Anti-IL16 Recombinant Antibody (A472) (CBMAB-AP10837LY)

Name: Mouse Anti-IL16 Recombinant Antibody (A472)
SKU: CBMAB-AP10837LY
Rating: 5 (1 reviews)

See all IL16 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

A472

Application

ELISA, WB

Immunogen

Fusion protein of IL-16

Specificity

Human

Antibody Isotype

IgG2b

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Purity

Affinity purity

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

Interleukin 16

Introduction

The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]

Entrez Gene ID

3603

UniProt ID

Q14005

Alternative Names

Interleukin 16

Function

E-AB-27571

Biological Process

Cytokine-mediated signaling pathway Source: ARUK-UCL
Immune response Source: ProtInc
Induction of positive chemotaxis Source: GO_Central
Leukocyte chemotaxis Source: GO_Central
Positive regulation of inflammatory response Source: ARUK-UCL
Positive regulation of interleukin-12 production Source: ARUK-UCL
Positive regulation of interleukin-1 alpha production Source: ARUK-UCL
Positive regulation of interleukin-6 production Source: ARUK-UCL
Positive regulation of neutrophil activation Source: ARUK-UCL
Regulation of calcium ion transport Source: CAFA

Cellular Location

Interleukin-16: Secreted
Isoform 1: Cytoplasm
Isoform 3: Nucleus; Cytoplasm

PTM

Isoform 3:
Synthesized as a chemo-attractant inactive precursor in hemopoietic tissues, and proteolytically cleaved by caspase-3 to yield IL-16.

Ma, C., Zhou, Y., Yi, W., Zhou, X., Guo, W., Xu, X., ... & Chen, D. (2022). Electroacupuncture of the Baihui and Shenting acupoints for vascular dementia in rats through the miR-81/IL-16/PSD-95 pathway. Annals of Translational Medicine, 10(10).

Ramirez, J., Bitterman, P., Basu, S., & Barua, A. (2022). Changes in IL-16 expression in the ovary during aging and its potential consequences to ovarian pathology. Journal of immunology research, 2022.

Liu, Y., Ma, X., & Liu, Y. (2021). Hsa_circ_0001326 regulates proliferation, migration, invasion, and EMT of HTR‐8/SVneo cells via increasing IL16 expression. American Journal of Reproductive Immunology, 86(5), e13484.

Wang, D., & Han, L. (2021). Downregulation of miR‑1184 serves as a diagnostic biomarker in neonatal sepsis and regulates LPS‑induced inflammatory response by inhibiting IL‑16 in monocytes. Experimental and therapeutic medicine, 21(4), 1-1.

Kawabata, K., Makino, T., Makino, K., Kajihara, I., Fukushima, S., & Ihn, H. (2020). IL-16 expression is increased in the skin and sera of patients with systemic sclerosis. Rheumatology, 59(3), 519-523.

Ahmad, S. F., Ansari, M. A., Nadeem, A., Bakheet, S. A., Al-Ayadhi, L. Y., & Attia, S. M. (2019). Elevated IL-16 expression is associated with development of immune dysfunction in children with autism. Psychopharmacology, 236, 831-838.

Huang, Y., Du, K. L., Guo, P. Y., Zhao, R. M., Wang, B., Zhao, X. L., & Zhang, C. Q. (2019). IL-16 regulates macrophage polarization as a target gene of mir-145-3p. Molecular Immunology, 107, 1-9.

Cheng, F., Liu, L., Zhang, H., Zhu, Y., Li, X., & Li, H. (2019). Association of IL-16 gene polymorphisms with the risk of developing type 2 diabetes mellitus in the Chinese Han population. Bioscience Reports, 39(8), BSR20190821.

Smith, S., Wu, P. W., Seo, J. J., Fernando, T., Jin, M., Contreras, J., ... & Jefferies, C. A. (2018). IL-16/miR-125a axis controls neutrophil recruitment in pristane-induced lung inflammation. JCI insight, 3(15).

Matalliotakis, M., Zervou, M. I., Eliopoulos, E., Matalliotaki, C., Rahmioglu, N., Kalogiannidis, I., ... & Goulielmos, G. N. (2018). The role of IL‑16 gene polymorphisms in endometriosis. international journal of molecular medicine, 41(3), 1469-1476.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-IL16 Recombinant Antibody (A472)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

Mouse Anti-IL16 Monoclonal Antibody (CBFYR0221) (CAT#: CBMAB-R0221-FY)

Mouse Anti-IL16 Recombinant Antibody (568) (CAT#: CBMAB-I1400-YY)

Mouse Anti-IL16 Monoclonal Antibody (CBFYR0222) (CAT#: CBMAB-R0222-FY)

Mouse Anti-IL16 Monoclonal Antibody (CBFYR0223) (CAT#: CBMAB-R0223-FY)

Mouse Anti-IL16 Monoclonal Antibody (CBFYR0220) (CAT#: CBMAB-R0220-FY)

Mouse Anti-IL16 Recombinant Antibody (14.1) (CAT#: CBMAB-I0402-YY)

Mouse Anti-IL16 Recombinant Antibody (CBYY-I1445) (CAT#: CBMAB-I2615-YY)

Mouse Anti-IL16 Recombinant Antibody (CBYY-I1267) (CAT#: CBMAB-I2436-YY)

Mouse Anti-IL16 Recombinant Antibody (A473) (CAT#: CBMAB-AP3735LY)

Mouse Anti-IL16 Recombinant Antibody (CF221) (CAT#: CBMAB-FT252LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry