Sign in or Register   Sign in or Register
  |  

Mouse Anti-IL9 Recombinant Antibody (9C1) (CBMAB-1044-LY)

This product is mouse antibody recognizes mouse IL-9. The antibody 9C1 immunoassay techniques such as: Neutralization.
See all IL9 antibodies

Summary

Host Animal
Mouse
Specificity
Mouse
Clone
9C1
Antibody Isotype
IgG2a
Application
Neutralization

Basic Information

Specificity
Mouse
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Interleukin 9
Introduction
Supports IL-2 independent and IL-4 independent growth of helper T-cells.
Entrez Gene ID
16198
UniProt ID
P15247
Alternative Names
P40; Il-9
Function
Supports IL-2 independent and IL-4 independent growth of helper T-cells.
Biological Process
B cell differentiationIEA:Ensembl
B cell proliferationIEA:Ensembl
Immunoglobulin mediated immune responseIEA:Ensembl
Inflammatory responseManual Assertion Based On ExperimentTAS:ProtInc
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathwayIEA:Ensembl
Positive regulation of cell growthIEA:Ensembl
Positive regulation of cell population proliferationManual Assertion Based On ExperimentTAS:ProtInc
Positive regulation of interleukin-5 productionISS:UniProtKB
Regulation of peptidyl-tyrosine phosphorylationIEA:Ensembl
Regulation of receptor signaling pathway via JAK-STATIEA:Ensembl
Cellular Location
Secreted

Kharwadkar, R., Ulrich, B. J., Chu, M., Koh, B., Hufford, M. M., Fu, Y., ... & Kaplan, M. H. (2023). ERG functionally overlaps with other Ets proteins in promoting TH9 cell expression of Il9 during allergic lung inflammation. The Journal of Immunology, 210(5), 537-546.

Sohn, J., Li, L., Zhang, L., Settem, R. P., Honma, K., Sharma, A., ... & Kirkwood, K. L. (2022). Porphyromonas gingivalis indirectly elicits intestinal inflammation by altering the gut microbiota and disrupting epithelial barrier function through IL9‐producing CD4+ T cells. Molecular Oral Microbiology, 37(2), 42-52.

Zha, L., Dong, J., Chen, Q., Liao, Y., Zhang, H., Xie, T., ... & Nie, S. (2022). Genetic association analysis between IL9 and coronary artery disease in a Chinese Han population. Cytokine, 150, 155761.

Chen, Q., Wang, W., Khanal, S., Han, J., Zhang, M., Chen, Y., ... & Wang, B. (2021). Transcriptome analysis reveals genes potentially related to high fiber strength in a Gossypium hirsutum line IL9 with Gossypium mustelinum introgression. Genome, 64(11), 985-995.

Sun, Y., Liu, S., Hu, R., Zhou, Q., & Li, X. (2020). Decreased placental IL9 and IL9R in preeclampsia impair trophoblast cell proliferation, invasion, and angiogenesis. Hypertension in Pregnancy, 39(3), 228-235.

Fu, Y., Wang, J., Panangipalli, G., Ulrich, B. J., Koh, B., Xu, C., ... & Kaplan, M. H. (2020). STAT5 promotes accessibility and is required for BATF-mediated plasticity at the Il9 locus. Nature communications, 11(1), 4882.

Lee, W. H., Jang, S. W., Kim, H. S., Kim, S. H., Heo, J. I., Kim, G. E., & Lee, G. R. (2019). BATF3 is sufficient for the induction of Il9 expression and can compensate for BATF during Th9 cell differentiation. Experimental & molecular medicine, 51(11), 1-12.

Abdul Qayum, A., Koh, B., Martin, R. K., Kenworthy, B. T., Kharwadkar, R., Fu, Y., ... & Kaplan, M. H. (2019). The Il9 CNS-25 regulatory element controls mast cell and basophil IL-9 production. The Journal of Immunology, 203(5), 1111-1121.

Li, L., Huang, S., Wang, H., Chao, K., Ding, L., Feng, R., ... & Zhang, S. (2018). Cytokine IL9 triggers the pathogenesis of inflammatory bowel disease through the miR21-CLDN8 pathway. Inflammatory Bowel Diseases, 24(10), 2211-2223.

Koh, B., Abdul Qayum, A., Srivastava, R., Fu, Y., Ulrich, B. J., Janga, S. C., & Kaplan, M. H. (2018). A conserved enhancer regulates Il9 expression in multiple lineages. Nature communications, 9(1), 4803.

Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-IL9 Recombinant Antibody (9C1)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare