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IL9

The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness. [provided by RefSeq, Jul 2008]

Full Name

Interleukin 9

Function

Supports IL-2 independent and IL-4 independent growth of helper T-cells.

Biological Process

B cell differentiationIEA:Ensembl
B cell proliferationIEA:Ensembl
Immunoglobulin mediated immune responseIEA:Ensembl
Inflammatory responseManual Assertion Based On ExperimentTAS:ProtInc
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathwayIEA:Ensembl
Positive regulation of cell growthIEA:Ensembl
Positive regulation of cell population proliferationManual Assertion Based On ExperimentTAS:ProtInc
Positive regulation of interleukin-5 productionISS:UniProtKB
Regulation of peptidyl-tyrosine phosphorylationIEA:Ensembl
Regulation of receptor signaling pathway via JAK-STATIEA:Ensembl

Cellular Location

Secreted

Anti-IL9 antibodies

Rat Anti-IL9 Recombinant Antibody (CBYY-I1251) (CBMAB-I2420-YY)

SDS

Target: IL9

Host: Rat

Antibody Isotype: IgG2

Specificity: Mouse

Clone: CBYY-I1251

Application*: WB

Mouse Anti-IL9 Recombinant Antibody (9C1) (CBMAB-I1830-YY)

SDS

Target: IL9

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Mouse

Clone: 9C1

Application*: BL

Mouse Anti-IL9 Recombinant Antibody (CBYY-I0740) (CBMAB-I1642-YY)

SDS

Target: IL9

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYY-I0740

Application*: N

Mouse Anti-IL9 Recombinant Antibody (623153) (CBMAB-I1507-YY)

SDS

Target: IL9

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 623153

Application*: F, MC

Rat Anti-IL9 Recombinant Antibody (CBYY-I0553) (CBMAB-I1237-YY)

SDS

Target: IL9

Host: Rat

Antibody Isotype: IgG2a, κ

Specificity: Mouse

Clone: CBYY-I0553

Application*: EC

Rat Anti-IL9 Recombinant Antibody (CBYY-I0450) (CBMAB-I1050-YY)

SDS

Target: IL9

Host: Rat

Antibody Isotype: IgG1

Specificity: Mouse

Clone: CBYY-I0450

Application*: F, IS, E

Mouse Anti-IL9 Recombinant Antibody (CBYY-I0327) (CBMAB-I0863-YY)

SDS

Target: IL9

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBYY-I0327

Application*: F

Mouse Anti-IL9 Recombinant Antibody (CBYY-I0326) (CBMAB-I0862-YY)

SDS

Target: IL9

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: CBYY-I0326

Application*: F, E

Mouse Anti-IL9 Recombinant Antibody (CBYY-I0325) (CBMAB-I0861-YY)

SDS

Target: IL9

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBYY-I0325

Application*: E, N, IS

Hamster Anti-IL9 Recombinant Antibody (CBYY-I0242) (CBMAB-I0629-YY)

SDS

Target: IL9

Host: Hamster

Antibody Isotype: IgG

Specificity: Mouse

Clone: CBYY-I0242

Application*: ED

Rat Anti-IL9 Recombinant Antibody (CBYY-I0241) (CBMAB-I0628-YY)

SDS

Target: IL9

Host: Rat

Antibody Isotype: IgG2b

Specificity: Mouse

Clone: CBYY-I0241

Application*: N

Rat Anti-IL9 Recombinant Antibody (222604) (CBMAB-I0627-YY)

SDS

Target: IL9

Host: Rat

Antibody Isotype: IgG2a

Specificity: Mouse

Clone: 222604

Application*: F, WB

Mouse Anti-IL9 Recombinant Antibody (A615) (CBMAB-AP3999LY)

SDS

Target: IL9

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: A615

Application*: ICC, IHC, IP, WB

Mouse Anti-IL9 Recombinant Antibody (A614) (CBMAB-AP10871LY)

SDS

Target: IL9

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: A614

Application*: ELISA, IHC, WB

Mouse Anti-IL9 Recombinant Antibody (CF243) (CBMAB-FT281LY)

SDS

Target: IL9

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CF243

Application*: ELISA, WB, IHC

Mouse Anti-IL9 Recombinant Antibody (1C9) (CBMAB-A4449-LY)

SDS

Target: IL9

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 1C9

Application*: E, E

Recombinant Rat Anti-IL9 Recombinant Antibody (RM9A4) (CBMAB-XB0613-YC)

SDS

Target: IL9

Host: Rat

Specificity: Mouse

Clone: RM9A4

Application*: FN

Recombinant Hamster Anti-IL9 Recombinant Antibody (D9302C12) (CBMAB-XB0612-YC)

SDS

Target: IL9

Host: Hamster

Antibody Isotype: IgG2, κ

Specificity: Mouse

Clone: D9302C12

Application*: FN

Recombinant Rat Anti-IL9 Recombinant Antibody (D8402E8) (CBMAB-XB0611-YC)

SDS

Target: IL9

Host: Rat

Antibody Isotype: IgG2a

Specificity: Mouse

Clone: D8402E8

Application*: E

Recombinant Mouse Anti-IL9 Recombinant Antibody (9D1) (CBMAB-XB0610-YC)

SDS

Target: IL9

Host: Mouse

Antibody Isotype: IgG2

Specificity: Human

Clone: 9D1

Application*: E

Recombinant Mouse Anti-IL9 Recombinant Antibody (9A4) (CBMAB-XB0608-YC)

SDS

Target: IL9

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 9A4

Application*: E, F

Mouse Anti-IL9 Recombinant Antibody (9C1) (CBMAB-1044-LY)

SDS

Target: IL9

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Mouse

Clone: 9C1

Application*: N

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

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