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Rabbit Anti-JCHAIN Recombinant Antibody (SP105) (CBMAB-0450-WJ)

This product is a rabbit antibody that recognizes JCHAIN. The antibody SP105 can be used for immunoassay techniques such as: IHC, IHC-P.
See all JCHAIN antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse
Clone
SP105
Antibody Isotype
IgG
Application
IHC, IHC-P

Basic Information

Immunogen
Synthetic peptide near the internal region of human J-chain.
Specificity
Human, Mouse
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
PREDICTED: similar to immunoglobulin J chain
Introduction
JCHAIN (Joining Chain Of Multimeric IgA And IgM) is a Protein Coding gene. Diseases associated with JCHAIN include Alpha Chain Disease and Mu Chain Disease. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Cell surface interactions at the vascular wall. Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.
Entrez Gene ID
Human3512
Mouse16069
UniProt ID
HumanP01591
MouseP01592
Alternative Names
IGJ; JCH; IGCJ
Function
Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces dimers and/or larger polymers. It also helps to bind these immunoglobulins to secretory component.
Biological Process
Adaptive immune responseManual Assertion Based On ExperimentIDA:UniProtKB
Antibacterial humoral responseManual Assertion Based On ExperimentIDA:UniProtKB
Glomerular filtrationManual Assertion Based On ExperimentIMP:UniProtKB
Humoral immune responseManual Assertion Based On ExperimentIBA:GO_Central
Immune response1 PublicationNAS:UniProtKB
Innate immune responseManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of respiratory burstManual Assertion Based On ExperimentIDA:UniProtKB
Protein-containing complex assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Retina homeostasisManual Assertion Based On ExperimentHEP:UniProtKB
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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