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JCHAIN

JCHAIN (Joining Chain Of Multimeric IgA And IgM) is a Protein Coding gene. Diseases associated with JCHAIN include Alpha Chain Disease and Mu Chain Disease. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Cell surface interactions at the vascular wall. Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.
Full Name
PREDICTED: similar to immunoglobulin J chain
Function
Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces dimers and/or larger polymers. It also helps to bind these immunoglobulins to secretory component.
Biological Process
Adaptive immune responseManual Assertion Based On ExperimentIDA:UniProtKB
Antibacterial humoral responseManual Assertion Based On ExperimentIDA:UniProtKB
Glomerular filtrationManual Assertion Based On ExperimentIMP:UniProtKB
Humoral immune responseManual Assertion Based On ExperimentIBA:GO_Central
Immune response1 PublicationNAS:UniProtKB
Innate immune responseManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of respiratory burstManual Assertion Based On ExperimentIDA:UniProtKB
Protein-containing complex assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Retina homeostasisManual Assertion Based On ExperimentHEP:UniProtKB
Cellular Location
Secreted

Anti-JCHAIN antibodies

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Target: JCHAIN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I2062
Application*: WB, IH
Target: JCHAIN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I2025
Application*: WB, IH, F
Target: JCHAIN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I1969
Application*: WB, F
Target: JCHAIN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I1957
Application*: WB, IH, F
Target: JCHAIN
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYY-I1391
Application*: WB, SE
Target: JCHAIN
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: SP105
Application*: IH, P
Target: JCHAIN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: Mc19-9
Application*: WB, E, IH, IP, C
Target: JCHAIN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3H7
Application*: P, WB
Target: JCHAIN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3H2560
Application*: E, IH, IP, WB
Target: JCHAIN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3F8
Application*: P, WB
Target: JCHAIN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2B9
Application*: F, WB
Target: JCHAIN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2B1
Application*: F, P, WB
Target: JCHAIN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLXJ-037
Application*: WB, P
Target: JCHAIN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLXJ-034
Application*: E, C, IP, WB
Target: JCHAIN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLXJ-036
Application*: IH, IP, WB
Target: JCHAIN
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLXJ-035
Application*: E, IH, IP, WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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