Sign in or Register   Sign in or Register
  |  

Rabbit Anti-MAPK8IP2 Recombinant Antibody (EG1715) (CBMAB-EN2053-LY)

The product is antibody recognizes JIP2. The antibody EG1715 immunoassay techniques such as: WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:5000.
See all MAPK8IP2 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
EG1715
Antibody Isotype
IgG
Application
WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:5000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from internal of human JIP2.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
mitogen-activated protein kinase 8 interacting protein 2
Introduction
This gene encodes a scaffold protein that is thought to be involved in the regulation of the c-Jun amino-terminal kinase signaling pathway. This protein has been shown to interact with and regulate the activity of MAPK8/JNK1 and MAP2K7/MKK7 kinases.
Entrez Gene ID
Human23542
Mouse60597
Rat315220
UniProt ID
HumanQ13387
MouseQ9ERE9
RatG3V9M2
Alternative Names
IB2; IB-2; JIP2; PRKM8IPL
Function
The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP2 inhibits IL1 beta-induced apoptosis in insulin-secreting cells. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins (By similarity).
Biological Process
Behavioral fear responseISS:BHF-UCL
Dendrite morphogenesisISS:BHF-UCL
Excitatory postsynaptic potentialISS:BHF-UCL
JNK cascadeIEA:Ensembl
MAPK cascadeIDA:MGI
Mating behaviorIEA:Ensembl
Negative regulation of apoptotic signaling pathwayManual Assertion Based On ExperimentIDA:UniProtKB
Nonassociative learningISS:BHF-UCL
Positive regulation of stress-activated MAPK cascadeIEA:Ensembl
Regulation of AMPA receptor activityISS:BHF-UCL
Regulation of JNK cascadeManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of NMDA receptor activityISS:BHF-UCL
Regulation of signaling receptor activityISS:BHF-UCL
Regulation of synaptic transmission, glutamatergicISS:BHF-UCL
Signal complex assemblyManual Assertion Based On ExperimentTAS:ProtInc
Social behaviorISS:BHF-UCL
Cellular Location
Cytoplasm
Accumulates in cell surface projections.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Rabbit Anti-MAPK8IP2 Recombinant Antibody (EG1715)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare