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Mouse Anti-Kel Recombinant Antibody (CBMAB-0475-LY)

This product is mouse antibody recognizes kel of drosophila. The antibody immunoassay techniques such as: IF, WB, IHC.
See all Kel antibodies

Summary

Host Animal
Mouse
Specificity
Common fruit fly, Frog
Antibody Isotype
IgG1
Application
IF, WB, IHC

Basic Information

Immunogen
Partial protein
Specificity
Common fruit fly, Frog
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Kell Blood Group, Metallo-Endopeptidase
Introduction
Component of ring canals that regulates the flow of cytoplasm between cells. May be involved in the regulation of cytoplasm flow from nurse cells to the oocyte during oogenesis. Binds actin.
Entrez Gene ID
35084
UniProt ID
Q04652
Alternative Names
9C; kelch 1B
Function
Zinc endopeptidase with endothelin-3-converting enzyme activity. Cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3.
Biological Process
Cellular calcium ion homeostasisIEA:Ensembl
Cellular magnesium ion homeostasisIEA:Ensembl
MyelinationIEA:Ensembl
Negative regulation of potassium ion transmembrane transportIEA:Ensembl
Protein processingManual Assertion Based On ExperimentIBA:GO_Central
Regulation of axon diameterIEA:Ensembl
Regulation of cell sizeIEA:Ensembl
Skeletal muscle fiber developmentIEA:Ensembl
VasoconstrictionManual Assertion Based On ExperimentTAS:HGNC-UCL
Cellular Location
Cell membrane. Spans the erythrocyte membrane, and is attached to the underlying cytoskeleton.
Topology
Cytoplasmic: 1-47
Helical: 48-67
Extracellular: 68-732
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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