Sign in or Register
  |  

Mouse Anti-KLHL25 Recombinant Antibody (1E9) (CBMAB-K1197-LY)

This product is antibody recognizes KLHL25. The antibody 1E9 immunoassay techniques such as: ELISA, WB.
Host Species
Mouse
Application
ELISA, WB
Immunogen
KLHL25 (AAH28100, 1 a.a. ~ 589 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Antibody Isotype
IgG2a, κ
Specificity
Human
Clone
1E9
Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Introduction
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for translational homeostasis. The BCR(KLHL25) ubiquitin ligase complex acts by mediating ubiquitination of hypophosphorylated EIF4EBP1 (4E-BP1): ubiquitination and subsequent degradation of hypophosphorylated EIF4EBP1 (4E-BP1) probably serves as a homeostatic mechanism to maintain translation and prevent eIF4E inhibition when eIF4E levels are low. The BCR(KLHL25) complex does not target EIF4EBP1 (4E-BP1) when it is hyperphosphorylated or associated with eIF4E.
Alternative Name
Kelch Like Family Member 25; Ectoderm-Neural Cortex Protein 2; Ectodermal-Neural Cortex 2; ENC-2; ENC2; BTB/POZ KELCH Domain Protein; Kelch-Like 25 (Drosophila); Kelch-Like Protein 25; Kelch-Like 25;
Entrez Gene ID
Ask a question We look forward to hearing from you.
0 reviews or Q&As
Loading...
Submit a review Submit a review and you will get a coupon.
0 reviews
Loading...
For Research Use Only. Not For Clinical Use.
Cat CBMAB-K1197-LY
Conjugates
Size
Price $
  ADD TO CART
Request bulk or custom quote
Second antibody and isotype control