Mouse Anti-LAIR2 Recombinant Antibody (CBT2196) (V2LY-0625-LY1272)

Elsayed, O. M., Abdelazim, S. A., Darwish, H. A., Shaker, O. G., & Senousy, M. A. (2023). Association of LncRNA-PAX8-AS1 and LAIR-2 polymorphisms along with their expression with clinical and subclinical hypothyroidism. Scientific Reports, 13(1), 6.

Pan, B., Wang, Z., Yao, Y., Ke, X., Shen, S., Chen, W., ... & Tang, N. (2023). TGF-β-p-STAT1-LAIR2 axis has a “self-rescue” role for exhausted CD8+ T cells in hepatocellular carcinoma. Cellular Oncology, 1-20.

Wang, P., Zhuang, W., Zheng, Z., Zhang, L., Zhang, X., & Chen, Q. (2023). Dissecting T-cell heterogeneity in esophageal squamous cell carcinoma reveals the potential role of LAIR2 in antitumor immunity. Clinical and Experimental Immunology, 214(1), 36-49.

Ly, D., Li, Q., Navab, R., Zeltz, C., Fang, L., Cabanero, M., ... & Zhang, L. (2022). Tumor-associated regulatory T cell expression of LAIR2 is prognostic in lung adenocarcinoma. Cancers, 14(1), 205.

Ramos, M. I. P., Tian, L., de Ruiter, E. J., Song, C., Paucarmayta, A., Singh, A., ... & Meyaard, L. (2021). Cancer immunotherapy by NC410, a LAIR-2 Fc protein blocking human LAIR-collagen interaction. Elife, 10, e62927.

Chen, Z., Yu, M., Yan, J., Guo, L., Zhang, B., Liu, S., ... & Xiao, Y. (2021). PNOC expressed by B cells in cholangiocarcinoma was survival related and LAIR2 could be a T cell exhaustion biomarker in tumor microenvironment: characterization of immune microenvironment combining single-cell and bulk sequencing technology. Frontiers in Immunology, 12, 647209.

Myint, H., Tian, L., Shaik, J., Barbu, E., Zhou, Q., Morawski, A., ... & Langermann, S. (2021). 487 NC410, a fusion protein of LAIR-2 (Leukocyte Associated Immunoglobulin-like Receptor) with human IgG1 Fc, is safe & tolerable with evidence of immune modulation in subjects with advanced solid tumors.

Horn, L., Tian, L., Flies, D., Liu, L., Langermann, S., Schlom, J., & Palena, C. (2020). 445 Blockade of the inhibitory collagen receptor LAIR-1 with NC410, a LAIR2-Fc fusion protein, enhances anti-tumor activity of the bifunctional fusion protein bintrafusp alfa.

Ly, D., Cabanero, M., Zhu, C., Tsao, M., & Zhang, L. (2018). P1. 04-05 elucidating the role of leukocyte-associated immunoglobin-like receptor 2 (LAIR2) in lung cancer development. Journal of Thoracic Oncology, 13(10), S526-S527.

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control