Human LAIR2 ELISA Kit (2) (V2LY-0626-LY4812)

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Tested Data
Datasheet
SDS
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Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Sensitivity
0.0097 ng/mL
Detection Range
0.02-4.5 ng/mL
Sample Type
Serum, Plasma, cell culture supernates
Specificity
Human
Assay Type
Sandwich
Reactivity
Human
Assay Time
1.5 h
Molecule Mass
16.3 kDa
Components
  • Pre-coated ELISA plate: 12 wells * 8 detachable strips
  • Standard solution: 0.5ml x1
  • Standard diluent: 3ml x1
  • Streptavidin-HRP: 6ml x1
  • Stop solution: 6ml x1
  • Substrate solution A: 6ml x1
  • Substrate solution B: 6ml x1
  • Wash buffer concentrate (25x): 20ml x1
  • Biotinylated antibody: 1ml x1

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 2-8°C
More Infomation

Target

Full Name
leukocyte associated immunoglobulin like receptor 2
Cellular Location
Secreted

Elsayed, O. M., Abdelazim, S. A., Darwish, H. A., Shaker, O. G., & Senousy, M. A. (2023). Association of LncRNA-PAX8-AS1 and LAIR-2 polymorphisms along with their expression with clinical and subclinical hypothyroidism. Scientific Reports, 13(1), 6.

Pan, B., Wang, Z., Yao, Y., Ke, X., Shen, S., Chen, W., ... & Tang, N. (2023). TGF-β-p-STAT1-LAIR2 axis has a “self-rescue” role for exhausted CD8+ T cells in hepatocellular carcinoma. Cellular Oncology, 1-20.

Wang, P., Zhuang, W., Zheng, Z., Zhang, L., Zhang, X., & Chen, Q. (2023). Dissecting T-cell heterogeneity in esophageal squamous cell carcinoma reveals the potential role of LAIR2 in antitumor immunity. Clinical and Experimental Immunology, 214(1), 36-49.

Ly, D., Li, Q., Navab, R., Zeltz, C., Fang, L., Cabanero, M., ... & Zhang, L. (2022). Tumor-associated regulatory T cell expression of LAIR2 is prognostic in lung adenocarcinoma. Cancers, 14(1), 205.

Ramos, M. I. P., Tian, L., de Ruiter, E. J., Song, C., Paucarmayta, A., Singh, A., ... & Meyaard, L. (2021). Cancer immunotherapy by NC410, a LAIR-2 Fc protein blocking human LAIR-collagen interaction. Elife, 10, e62927.

Chen, Z., Yu, M., Yan, J., Guo, L., Zhang, B., Liu, S., ... & Xiao, Y. (2021). PNOC expressed by B cells in cholangiocarcinoma was survival related and LAIR2 could be a T cell exhaustion biomarker in tumor microenvironment: characterization of immune microenvironment combining single-cell and bulk sequencing technology. Frontiers in Immunology, 12, 647209.

Myint, H., Tian, L., Shaik, J., Barbu, E., Zhou, Q., Morawski, A., ... & Langermann, S. (2021). 487 NC410, a fusion protein of LAIR-2 (Leukocyte Associated Immunoglobulin-like Receptor) with human IgG1 Fc, is safe & tolerable with evidence of immune modulation in subjects with advanced solid tumors.

Horn, L., Tian, L., Flies, D., Liu, L., Langermann, S., Schlom, J., & Palena, C. (2020). 445 Blockade of the inhibitory collagen receptor LAIR-1 with NC410, a LAIR2-Fc fusion protein, enhances anti-tumor activity of the bifunctional fusion protein bintrafusp alfa.

Ly, D., Cabanero, M., Zhu, C., Tsao, M., & Zhang, L. (2018). P1. 04-05 elucidating the role of leukocyte-associated immunoglobin-like receptor 2 (LAIR2) in lung cancer development. Journal of Thoracic Oncology, 13(10), S526-S527.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Human Recombinant LAIR2 protein, His Tag (CAT#: V2LY-0526-LY5243)

Human Recombinant LAIR2 protein (CAT#: V2LY-0526-LY5244)

Human Recombinant LAIR2 protein-1 (CAT#: V2LY-0526-LY5245)

Human LAIR2 ELISA Kit (CAT#: V2LY-0626-LY2772)

Related Products

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Human Recombinant LAIR2 protein (CAT#: V2LY-0526-LY5244)

Rabbit Anti-LAIR2 Recombinant Antibody (CBYJL-1067) (CAT#: CBMAB-L0500-YJ)

Human LAIR2 ELISA Kit (CAT#: V2LY-0626-LY2772)

Mouse Anti-LAIR2 Recombinant Antibody (CBYJL-1068) (CAT#: CBMAB-L0504-YJ)

Mouse Anti-LAIR2 Recombinant Antibody (319701) (CAT#: CBMAB-L0502-YJ)

Human Recombinant LAIR2 protein, His Tag (CAT#: V2LY-0526-LY5243)

Mouse Anti-LAIR2 Recombinant Antibody (CBT2196) (CAT#: V2LY-0625-LY1272)

Human Recombinant LAIR2 protein-1 (CAT#: V2LY-0526-LY5245)

Isotype control

For research use only. Not intended for any clinical use.

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