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Rabbit Anti-MELTF (C-terminus) Recombinant Antibody (CBFYM-2054) (CBMAB-M2235-FY)

This product is rabbit antibody that recognizes MELTF. The antibody CBFYM-2054 can be used for immunoassay techniques such as: WB.
See all MELTF antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
CBFYM-2054
Application
WB

Basic Information

Immunogen
KLH conjugated synthetic peptide from C-terminal region of human MFI2.Immunogen type: Synthetic peptide
Specificity
Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
C-terminus

Target

Full Name
Melanotransferrin
Introduction
The protein encoded by this gene is a cell-surface glycoprotein found on melanoma cells. The protein shares sequence similarity and iron-binding properties with members of the transferrin superfamily. The importance of the iron binding function has not yet been identified. This gene resides in the same region of chromosome 3 as members of the transferrin superfamily. Alternative splicing results in two transcript variants.
Entrez Gene ID
4241
UniProt ID
P08582
Alternative Names
Melanotransferrin; Antigen P97 (Melanoma Associated) Identified By Monoclonal Antibodies 133.2 And 96.5; Membrane-Bound Transferrin-Like Protein; Melanoma-Associated Antigen P97; MAP97; MFI2
Function
Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc.
Biological Process
Iron ion homeostasis Source: UniProtKB-KW
Iron ion transport Source: UniProtKB
Negative regulation of substrate adhesion-dependent cell spreading Source: UniProtKB
Positive regulation of extracellular matrix disassembly Source: UniProtKB
Positive regulation of plasminogen activation Source: UniProtKB
Cellular Location
Cell membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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