MELTF

The protein encoded by this gene is a cell-surface glycoprotein found on melanoma cells. The protein shares sequence similarity and iron-binding properties with members of the transferrin superfamily. The importance of the iron binding function has not yet been identified. This gene resides in the same region of chromosome 3 as members of the transferrin superfamily. Alternative splicing results in two transcript variants. [provided by RefSeq, Jul 2008]
Full Name
Melanotransferrin
Function
Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc.
Biological Process
Iron ion homeostasis Source: UniProtKB-KW
Iron ion transport Source: UniProtKB
Negative regulation of substrate adhesion-dependent cell spreading Source: UniProtKB
Positive regulation of extracellular matrix disassembly Source: UniProtKB
Positive regulation of plasminogen activation Source: UniProtKB
Cellular Location
Cell membrane
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Anti-MELTF antibodies

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Mouse Anti-MELTF Recombinant Antibody (214D4) (CBMAB-C4383-LY)

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Target: MELTF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 214D4
Application*: P, C
Datasheet SDS

Mouse Anti-MELTF Recombinant Antibody (SHM72) (CBMAB-C12048-LY)

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Target: MELTF
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: SHM72
Application*: F
Datasheet SDS

Human Anti-MELTF Recombinant Antibody (CBXC-0921) (CBMAB-C2036-CQ)

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Target: MELTF
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0921
Application*: F
Datasheet SDS

Mouse Anti-MELTF Recombinant Antibody (CBFYC-2947) (CBMAB-C3023-FY)

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Target: MELTF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-2947
Application*: P, C
Datasheet SDS

Rabbit Anti-MELTF Recombinant Antibody (CBFYM-2060) (CBMAB-M2241-FY)

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Target: MELTF
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBFYM-2060
Application*: E, WB
Datasheet SDS

Rabbit Anti-MELTF (N-terminus) Recombinant Antibody (CBFYM-2059) (CBMAB-M2240-FY)

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Target: MELTF
Host: Rabbit
Specificity: Human
Clone: CBFYM-2059
Application*: IH
Datasheet SDS

Mouse Anti-MELTF (AA 1-302) Recombinant Antibody (CBFYM-2058) (CBMAB-M2239-FY)

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Target: MELTF
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYM-2058
Application*: WB
Datasheet SDS

Mouse Anti-MELTF Recombinant Antibody (CBFYM-2057) (CBMAB-M2238-FY)

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Target: MELTF
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBFYM-2057
Application*: WB, E, F
Datasheet SDS

Mouse Anti-MELTF (AA 21-302) Recombinant Antibody (CBFYM-2056) (CBMAB-M2237-FY)

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Target: MELTF
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: CBFYM-2056
Application*: E, WB
Datasheet SDS

Mouse Anti-MELTF (AA 1-711) Recombinant Antibody (CBFYM-2055) (CBMAB-M2236-FY)

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Target: MELTF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-2055
Application*: WB
Datasheet SDS

Rabbit Anti-MELTF (C-terminus) Recombinant Antibody (CBFYM-2054) (CBMAB-M2235-FY)

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Target: MELTF
Host: Rabbit
Specificity: Human
Clone: CBFYM-2054
Application*: WB
Datasheet SDS

Rabbit Anti-MELTF (AA 627-655) Recombinant Antibody (CBFYM-0455) (CBMAB-M0573-FY)

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Target: MELTF
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYM-0455
Application*: E, WB
Datasheet SDS

Mouse Anti-MELTF (AA 1-711) Recombinant Antibody (CBFYM-0218) (CBMAB-M0261-FY)

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Target: MELTF
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-0218
Application*: F
Datasheet SDS

Human Recombinant MFI2 protein, His Tag (V2LY-0526-LY5530)

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Target: MELTF
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-708
Tag: His Tag
Datasheet SDS

Mouse Recombinant MFI2 protein, His Tag (V2LY-0526-LY8664)

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Target: MELTF
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-708
Tag: His Tag
Datasheet SDS

Mouse Recombinant MFI2 protein, hFc Tag (V2LY-0526-LY8663)

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Target: MELTF
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-708
Tag: hFc Tag
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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