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Mouse Anti-MYL1 Recombinant Antibody (MY-38) (CBMAB-AO762LY)

The product is antibody recognizes MYL1. The antibody MY-38 immunoassay techniques such as: ELISA, WB, IHC.
See all MYL1 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Rat, Mouse, Rabbit
Clone
MY-38
Antibody Isotype
IgG1
Application
ELISA, WB, IHC

Basic Information

Immunogen
Rabbit muscle myosin.
Specificity
Human, Rat, Mouse, Rabbit
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
2% BSA
Preservative
0.09% sodium azide
Concentration
1 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Myosin Light Chain 1
Introduction
Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain expressed in fast skeletal muscle. Two transcript variants have been identified for this gene. [provided by RefSeq, Jul 2008]
Entrez Gene ID
Human4632
Mouse17901
Rat56781
Rabbit100009400
UniProt ID
HumanP05976
MouseP05977
RatP02600
RabbitP02602
Alternative Names
Myosin light chain 1/3, skeletal muscle isoform; MLC1/MLC3; MLC1F/MLC3F; Myosin light chain alkali 1/2; Myosin light chain A1/A2; MYL1
Function
Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function.
Biological Process
Muscle contraction Source: BHF-UCL
Muscle filament sliding Source: BHF-UCL
Cellular Location
Cytoskeleton
muscle myosin complex
myosin II complex
Cytosol
Other locations
contractile fiber
myofibril
sarcomere
Involvement in disease
Myopathy, congenital, with fast-twitch type II fiber atrophy (MYOFTA):
An autosomal recessive congenital myopathy characterized by decreased fetal movements, severe muscle weakness and respiratory failure. Additional features include delayed motor development, areflexia, facial weakness, normal eye movements, head lag, and mild contractures. Skeletal muscle biopsy shows variation in fiber size with atrophy of the fast-twitch type II fibers.
PTM
Isoform MLC3:
Acetylated at position 2.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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