Mouse Anti-NCOR1 Recombinant Antibody (CBT932) (V2LY-0625-LY3171)
Basic Information
| Application | Note |
| ELISA | 1:10,000 |
| IHC | 1:200-1:1,000 |
| WB | 1:500-1:2,000 |
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Part of a complex which promotes histone deacetylation and the formation of repressive chromatin structures which may impede the access of basal transcription factors. Participates in the transcriptional repressor activity produced by BCL6. Recruited by ZBTB7A to the androgen response elements/ARE on target genes, negatively regulates androgen receptor signaling and androgen-induced cell proliferation (PubMed:20812024).
Mediates the NR1D1-dependent repression and circadian regulation of TSHB expression (By similarity).
The NCOR1-HDAC3 complex regulates the circadian expression of the core clock gene ARTNL/BMAL1 and the genes involved in lipid metabolism in the liver (By similarity).
Locomotor rhythm Source: UniProtKB
Negative regulation of androgen receptor signaling pathway Source: UniProtKB
Negative regulation of fatty acid metabolic process Source: BHF-UCL
Negative regulation of glycolytic process Source: BHF-UCL
Negative regulation of JNK cascade Source: UniProtKB
Negative regulation of production of miRNAs involved in gene silencing by miRNA Source: BHF-UCL
Negative regulation of transcription, DNA-templated Source: UniProtKB
Negative regulation of transcription by RNA polymerase II Source: UniProtKB
Regulation of transcription by RNA polymerase II Source: GO_Central
Spindle assembly Source: UniProtKB
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
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Mouse Anti-NCOR1 Recombinant Antibody (7A7A9) (CAT#: CBMAB-N1470-WJ)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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