Mouse Anti-PACSIN3 Recombinant Antibody (CBXS-4026) (CBMAB-S1287-CQ)

Name: Mouse Anti-PACSIN3 Recombinant Antibody (CBXS-4026)
SKU: CBMAB-S1287-CQ
Rating: 5 (1 reviews)

See all PACSIN3 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBXS-4026

Application

FC, WB

Immunogen

Full length recombinant protein of human PACSIN3 (NP_057307)

Specificity

Human

Antibody Isotype

IgG1

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.3, 1% BSA, 50% glycerol

Preservative

0.02% sodium azide

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

protein kinase C and casein kinase substrate in neurons 3

Entrez Gene ID

29763

UniProt ID

Q9UKS6

Alternative Names

SDPIII

Function

Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity (By similarity).

Biological Process

Cytoskeleton organizationManual Assertion Based On ExperimentIBA:GO_Central
EndocytosisIEA:UniProtKB-KW
Negative regulation of calcium ion transportISS:UniProtKB
Negative regulation of endocytosisISS:UniProtKB
Plasma membrane tubulationManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of membrane protein ectodomain proteolysisManual Assertion Based On ExperimentIMP:BHF-UCL
Regulation of endocytosisManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cytoplasm
Cell membrane
Detected at the inner aspect of the plasma membrane in myotubes.

PTM

Phosphorylated by casein kinase 2 (CK2) and protein kinase C (PKC).

Han, G. H., Shim, J. E., Yun, H., Kim, J., Kim, J. H., & Cho, H. (2022). RNA sequencing and bioinformatics analysis revealed PACSIN3 as a potential novel biomarker for platinum resistance in epithelial ovarian cancer. The journal of gene medicine, 24(11), e3452.

Han, G. H., Cho, H., Yun, H., & Kim, J. H. (2022). PACSIN3 is a novel biomarker for platinum resistance BRCA mutated platinum resistance epithelial ovarian cancer.

Milewska, M., Domoradzki, T., Majewska, A., Błaszczyk, M., Gajewska, M., Hulanicka, M., & Grzelkowska-Kowalczyk, K. (2020). Interleukin-6 affects pacsin3, ephrinA4 expression and cytoskeletal proteins in differentiating primary skeletal myoblasts through transcriptional and post-transcriptional mechanisms. Cell and tissue research, 380, 155-172.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-PACSIN3 Recombinant Antibody (CBXS-4026)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-PACSIN3 Recombinant Antibody (2A3) (CAT#: CBMAB-P0634-YC)

Mouse Anti-PACSIN3 Recombinant Antibody (2A6) (CAT#: CBMAB-P0635-YC)

Mouse Anti-PACSIN3 Recombinant Antibody (4F8) (CAT#: CBMAB-P0637-YC)

Mouse Anti-PACSIN3 Recombinant Antibody (2D7) (CAT#: CBMAB-P0636-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry