Mouse Anti-PAPPA Monoclonal Antibody (CBFYR0627) (CBMAB-R0627-FY)

Name: Mouse Anti-PAPPA Monoclonal Antibody (CBFYR0627)
SKU: CBMAB-R0627-FY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBFYR0627

Application

ELISA

Immunogen

Human purified PAPP-A from retroplacental blood

Specificity

Human

Antibody Isotype

IgG1, κ

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Ascites

Preservative

0.05% Sodium azide

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

Pappalysin 1

Introduction

Pappalysin-1, also known as pregnancy-associated plasma protein A, is a protein encoded by the PAPPA gene in humans.

Entrez Gene ID

5069

UniProt ID

Q13219

Alternative Names

PAPPA

Function

Metalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF.

Biological Process

Cellular protein metabolic processTAS:Reactome
Female pregnancyManual Assertion Based On ExperimentTAS:ProtInc
Response to follicle-stimulating hormoneIEA:Ensembl
Response to glucocorticoidIEA:Ensembl

Cellular Location

Secreted

PTM

There appear to be no free sulfhydryl groups.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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