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Mouse Anti-PLD2 Recombinant Antibody (1C5) (CBMAB-P2076-YC)

Provided herein is a Mouse monoclonal antibody against Human Phospholipase D2. The antibody can be used for immunoassay techniques, such as WB, IP, ELISA.
See all PLD2 antibodies
Published Data
Fig.1 Representative western blot for PLD2 and band densitometry (see S1B Fig for complete blot).
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Summary

Host Animal
Mouse
Specificity
Human, Rat
Clone
1C5
Antibody Isotype
IgG
Application
WB, IP, ELISA

Basic Information

Specificity
Human, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
phospholipase D2
Introduction
PLD2 catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. The activity of the encoded enzyme is enhanced by phosphatidylinositol 4,5-bisphosphate and ADP-ribosylation factor-1. This protein localizes to the peripheral membrane and may be involved in cytoskeletal organization, cell cycle control, transcriptional regulation, and/or regulated secretion.
Entrez Gene ID
Human5338
Rat25097
UniProt ID
HumanO14939
RatP70498
Alternative Names
HPLD2; PLD1C
Function
Function as phospholipase selective for phosphatidylcholine (PubMed:9582313).
May have a role in signal-induced cytoskeletal regulation and/or endocytosis (By similarity).
Biological Process
Cytoskeleton organizationManual Assertion Based On ExperimentTAS:ProtInc
Fc-gamma receptor signaling pathway involved in phagocytosisTAS:Reactome
Inositol lipid-mediated signalingIEA:InterPro
Phosphatidic acid biosynthetic processTAS:Reactome
Phospholipid catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Regulation of vesicle-mediated transportManual Assertion Based On ExperimentIBA:GO_Central
Small GTPase mediated signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Synaptic vesicle recyclingManual Assertion Based On ExperimentTAS:ParkinsonsUK-UCL
Cellular Location
Cell membrane
PTM
Phosphorylated by FGR.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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