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Rabbit Anti-PLD2 Recombinant Antibody (E1Y9G) (CBMAB-CP2018-LY)


See all PLD2 antibodies
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Summary

Host Animal
Rabbit
Specificity
Human
Clone
E1Y9G
Antibody Isotype
IgG
Application
WB

Basic Information

Immunogen
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala880 of human PLD2 protein.
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
100 µg/ml BSA, 50% glycerol
Preservative
0.02% sodium azide
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
phospholipase D2
Entrez Gene ID
5338
UniProt ID
O14939
Function
Function as phospholipase selective for phosphatidylcholine (PubMed:9582313).
May have a role in signal-induced cytoskeletal regulation and/or endocytosis (By similarity).
Biological Process
Cytoskeleton organizationManual Assertion Based On ExperimentTAS:ProtInc
Fc-gamma receptor signaling pathway involved in phagocytosisTAS:Reactome
Inositol lipid-mediated signalingIEA:InterPro
Phosphatidic acid biosynthetic processTAS:Reactome
Phospholipid catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Regulation of vesicle-mediated transportManual Assertion Based On ExperimentIBA:GO_Central
Small GTPase mediated signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Synaptic vesicle recyclingManual Assertion Based On ExperimentTAS:ParkinsonsUK-UCL
Cellular Location
Cell membrane
PTM
Phosphorylated by FGR.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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