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Mouse Anti-PLD2 Recombinant Antibody (7E4D9) (CBMAB-P2077-YC)

Provided herein is a Mouse monoclonal antibody against Human Phospholipase D2. The antibody can be used for immunoassay techniques, such as ELISA, WB, IHC-P, IF, ICC, FC.
See all PLD2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
7E4D9
Antibody Isotype
IgG1
Application
ELISA, WB, IHC-P, IF, ICC, FC

Basic Information

Immunogen
Recombinant fragment of human PLD2 (AA 834-933) expressed in E. coli
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS with 0.05% sodium azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
phospholipase D2
Introduction
PLD2 catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. The activity of the encoded enzyme is enhanced by phosphatidylinositol 4,5-bisphosphate and ADP-ribosylation factor-1. This protein localizes to the peripheral membrane and may be involved in cytoskeletal organization, cell cycle control, transcriptional regulation, and/or regulated secretion.
Entrez Gene ID
5338
UniProt ID
O14939
Alternative Names
HPLD2; PLD1C
Function
Function as phospholipase selective for phosphatidylcholine (PubMed:9582313).
May have a role in signal-induced cytoskeletal regulation and/or endocytosis (By similarity).
Biological Process
Cytoskeleton organizationManual Assertion Based On ExperimentTAS:ProtInc
Fc-gamma receptor signaling pathway involved in phagocytosisTAS:Reactome
Inositol lipid-mediated signalingIEA:InterPro
Phosphatidic acid biosynthetic processTAS:Reactome
Phospholipid catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Regulation of vesicle-mediated transportManual Assertion Based On ExperimentIBA:GO_Central
Small GTPase mediated signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Synaptic vesicle recyclingManual Assertion Based On ExperimentTAS:ParkinsonsUK-UCL
Cellular Location
Cell membrane
PTM
Phosphorylated by FGR.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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