Mouse Anti-PLSCR3 Recombinant Antibody (4D11) (CBMAB-A6819-LY)
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Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Plays an important role in mitochondrial respiratory function, morphology, and apoptotic response (PubMed:14573790, PubMed:17226776, PubMed:18358005, PubMed:12649167).
Mediates the translocation of cardiolipin from the mitochondrial inner membrane to outer membrane enhancing t-Bid induced cytochrome c release and apoptosis (PubMed:14573790, PubMed:17226776, PubMed:18358005).
Enhances TNFSF10-induced apoptosis by regulating the distribution of cardiolipin in the mitochondrial membrane resulting in increased release of apoptogenic factors and consequent amplification of the activity of caspases (PubMed:18491232).
Regulates cardiolipin de novo biosynthesis and its resynthesis (PubMed:16939411).
Cardiolipin biosynthetic processManual Assertion Based On ExperimentIMP:UniProtKB
Cellular response to lipopolysaccharideIEA:Ensembl
Cholesterol homeostasisIEA:Ensembl
Glucose homeostasisIEA:Ensembl
Plasma membrane phospholipid scramblingManual Assertion Based On ExperimentIBA:GO_Central
Regulation of apoptotic processManual Assertion Based On ExperimentIMP:UniProtKB
Regulation of release of cytochrome c from mitochondriaManual Assertion Based On ExperimentIMP:UniProtKB
Mitochondrion inner membrane
Nucleus
Palmitoylation regulates its localization to the cell membrane or the nucleus; trafficking to the cell membrane is dependent upon palmitoylation whereas in the absence of palmitoylation, localizes to the nucleus.
Helical: 266-282
Palmitoylation regulates its localization to the cell membrane or the nucleus; trafficking to the cell membrane is dependent upon palmitoylation whereas in the absence of palmitoylation, localizes to the nucleus.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Antibody Pairs
PLSCR3 Matched Antibody Pair (893) (CAT#: APMAB-893LY)
Related Products
Mouse Anti-PLSCR3 Recombinant Antibody (1B5) (CAT#: CBMAB-A6816-LY)
Mouse Anti-PLSCR3 Recombinant Antibody (CBYC-P456) (CAT#: CBMAB-P2183-YC)
Mouse Anti-PLSCR3 Recombinant Antibody (4F5) (CAT#: CBMAB-A6820-LY)
PLSCR3 Matched Antibody Pair (893) (CAT#: APMAB-893LY)
Mouse Anti-PLSCR3 Recombinant Antibody (4B5) (CAT#: CBMAB-P2181-YC)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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