Sign in or Register   Sign in or Register
  |  

Mouse Anti-PON3 Recombinant Antibody (1F12) (CBMAB-P2404-YC)

Provided herein is a Mouse monoclonal antibody against Human Paraoxonase 3. The antibody can be used for immunoassay techniques, such as WB, IHC.
See all PON3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1F12
Antibody Isotype
IgG1
Application
WB, IHC

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Paraoxonase 3
Introduction
PON3 is a member of the paraoxonase family and lies in a cluster on chromosome 7 with the other two family members. The encoded protein is secreted into the bloodstream and associates with high-density lipoprotein (HDL). The protein also rapidly hydrolyzes lactones and can inhibit the oxidation of low-density lipoprotein (LDL), a function that is believed to slow the initiation and progression of atherosclerosis.
Entrez Gene ID
5446
UniProt ID
Q15166
Alternative Names
Arylesterase 3; Serum Paraoxonase/Lactonase 3
Function
Has low activity towards the organophosphate paraxon and aromatic carboxylic acid esters. Rapidly hydrolyzes lactones such as statin prodrugs (e.g. lovastatin). Hydrolyzes aromatic lactones and 5- or 6-member ring lactones with aliphatic substituents but not simple lactones or those with polar substituents.
Biological Process
Aromatic compound catabolic processManual Assertion Based On ExperimentIDA:BHF-UCL
Carboxylic acid catabolic processManual Assertion Based On ExperimentIDA:BHF-UCL
Coumarin catabolic processIEA:Ensembl
Establishment of localization in cellIEA:Ensembl
Negative regulation of superoxide anion generationIEA:Ensembl
Phenylacetate catabolic processIEA:Ensembl
Renal sodium ion transportIEA:Ensembl
Response to toxic substanceManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Secreted, extracellular space
PTM
The signal sequence is not cleaved.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-PON3 Recombinant Antibody (1F12)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare