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Rat Anti-PON3 Recombinant Antibody (MM1075-29P7) (CBMAB-0684CQ)

This product is a rat antibody that recognizes PON3. The antibody MM1075-29P7 can be used for immunoassay techniques such as: WB.
See all PON3 antibodies

Summary

Host Animal
Rat
Specificity
Human, Mouse, Rat
Clone
MM1075-29P7
Antibody Isotype
IgG2
Application
WB

Basic Information

Immunogen
Recombinant fragment from Human PON3 aa 30-354
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG2
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Paraoxonase 3
Introduction
This gene is a member of the paraoxonase family and lies in a cluster on chromosome 7 with the other two family members. Has low activity towards the organophosphate paraxon and aromatic carboxylic acid esters. Rapidly hydrolyzes lactones such as statin prodrugs (e.g. lovastatin). Hydrolyzes aromatic lactones and 5- or 6-member ring lactones with aliphatic substituents but not simple lactones or those with polar substituents.
Entrez Gene ID
Human5446
Mouse269823
Rat312086
UniProt ID
HumanQ15166
MouseQ62087
RatQ68FP2
Alternative Names
Paraoxonase 3
Function
Has low activity towards the organophosphate paraxon and aromatic carboxylic acid esters. Rapidly hydrolyzes lactones such as statin prodrugs (e.g. lovastatin). Hydrolyzes aromatic lactones and 5- or 6-member ring lactones with aliphatic substituents but not simple lactones or those with polar substituents.
Biological Process
Aromatic compound catabolic processManual Assertion Based On ExperimentIDA:BHF-UCL
Carboxylic acid catabolic processManual Assertion Based On ExperimentIDA:BHF-UCL
Coumarin catabolic processIEA:Ensembl
Establishment of localization in cellIEA:Ensembl
Negative regulation of superoxide anion generationIEA:Ensembl
Phenylacetate catabolic processIEA:Ensembl
Renal sodium ion transportIEA:Ensembl
Response to toxic substanceManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Secreted, extracellular space
PTM
The signal sequence is not cleaved.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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