Human Recombinant PON3 (50 Ser/Asn) protein, His Tag (V2LY-0526-LY6255)

Name: Human Recombinant PON3 (50 Ser/Asn) protein, His Tag
SKU: V2LY-0526-LY6255
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

Baculovirus-Insect Cells

Protein Species

Human

Tag

His Tag

Protein Construction

This product is Human Recombinant PON3 (50 Ser/Asn) protein, His Tag consist of Amino Acid: 1-354, 50/ and predicts a molecular mass of 42 kDa.

Molecule Mass

42 kDa

Sequence

Amino Acid: 1-354, 50/

Species

Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

>85% as determined by SDS-PAGE

Endotoxin

Please contact us for more information.

Format

Lyophilized

Reconstitution

Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.

Buffer

Lyophilized from sterile Tris

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

Paraoxonase 3

Function

Has low activity towards the organophosphate paraxon and aromatic carboxylic acid esters. Rapidly hydrolyzes lactones such as statin prodrugs (e.g. lovastatin). Hydrolyzes aromatic lactones and 5- or 6-member ring lactones with aliphatic substituents but not simple lactones or those with polar substituents.

Biological Process

Aromatic compound catabolic processManual Assertion Based On ExperimentIDA:BHF-UCL
Carboxylic acid catabolic processManual Assertion Based On ExperimentIDA:BHF-UCL
Coumarin catabolic processIEA:Ensembl
Establishment of localization in cellIEA:Ensembl
Negative regulation of superoxide anion generationIEA:Ensembl
Phenylacetate catabolic processIEA:Ensembl
Renal sodium ion transportIEA:Ensembl
Response to toxic substanceManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Secreted, extracellular space

PTM

The signal sequence is not cleaved.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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