Sign in or Register   Sign in or Register
  |  

Mouse Anti-PPP1R10 Antibody (V2-5098) (CBMAB-0846-YC)

Provided herein are mouse monoclonal antibodies against Human PPP1R10. The antibody clone 1A2 can be used for immunoassay techniques, such as WB and MA.
See all PPP1R10 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
V2-5098
Antibody Isotype
IgG2b
Application
WB, MA

Basic Information

Immunogen
Recombinant protein
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
PPP1R10
Introduction
PPP1R10 (serine/threonine-protein phosphatase 1 regulatory subunit 10) is a protein phosphatase 1 binding protein. PPP1R10 plays a role in many cellular processes including cell cycle progression, DNA repair and apoptosis by regulating the activity of protein phosphatase 1.
Entrez Gene ID
5514
UniProt ID
Q96QC0
Alternative Names
p99; FB19; R111; CAT53; PNUTS; PP1R10
Function
Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) homopolymers (By similarity).
Biological Process
Negative regulation of cardiac muscle cell apoptotic processManual Assertion Based On ExperimentIDA:BHF-UCL
Negative regulation of mitotic DNA damage checkpointManual Assertion Based On ExperimentIGI:BHF-UCL
Positive regulation of telomere maintenanceManual Assertion Based On ExperimentIMP:BHF-UCL
Protein import into nucleusManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Nucleus
Found in discrete nucleoplasmic bodies and within nucleoli. Associates with chromatin during interphase, excluded from condensed chromosomes during early mitosis and is reloaded onto chromosomes at the late telophase (By similarity).
PTM
Phosphorylated on Ser-398 by PKA within the region necessary for interaction with PPP1CA.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-PPP1R10 Antibody (V2-5098)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare