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Mouse Anti-PPP1R13L Antibody (2G4) (CBMAB-0848-YC)

Provided herein are mouse monoclonal antibodies against Human PPP1R13L. The antibody clone 2G4 can be used for immunoassay techniques, such as IP and MA.
See all PPP1R13L antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2G4
Antibody Isotype
IgG2b
Application
IP, MA

Basic Information

Immunogen
Recombinant protein
Specificity
Human
Antibody Isotype
IgG2b
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
PPP1R13L
Introduction
PPP1R13L (relA-associated inhibitor) is a protein that in humans is encoded by the PPP1R13L gene. PPP1R13L has been shown to interact with Sp1 transcription factor and RELA.
Entrez Gene ID
10848
UniProt ID
Q8WUF5
Alternative Names
IASPP; RAI
Function
Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis (PubMed:12524540).
Biological Process
Apoptotic processIEA:UniProtKB-KW
Cardiac muscle contractionIEA:Ensembl
Cardiac right ventricle morphogenesisIEA:Ensembl
Embryonic camera-type eye developmentIEA:Ensembl
Hair cycleIEA:Ensembl
Multicellular organism growthIEA:Ensembl
Multicellular organismal homeostasisIEA:Ensembl
Negative regulation of transcription by RNA polymerase IIIEA:Ensembl
Positive regulation of cell differentiationManual Assertion Based On ExperimentIBA:GO_Central
Post-embryonic developmentIEA:Ensembl
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Ventricular cardiac muscle tissue developmentIEA:Ensembl
Cellular Location
Cytoplasm
Nucleus
Predominantly cytoplasmic but also nuclear.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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