Mouse Anti-PPP1R13L Recombinant Antibody (CBYY-I1479) (CBMAB-I2649-YY)

Name: Mouse Anti-PPP1R13L Recombinant Antibody (CBYY-I1479)
SKU: CBMAB-I2649-YY
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBYY-I1479

Application

WB, IP, IF, ELISA

Specificity

Human

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

PPP1R13L

Introduction

IASPP is one of the most evolutionarily conserved inhibitors of p53, whereas ASPP1 and ASPP2 (MIM 602143) are activators of p53.

Entrez Gene ID

10848

UniProt ID

Q8WUF5

Alternative Names

RAI; RAI4; IASPP; NKIP1

Function

Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis (PubMed:12524540).

Biological Process

Apoptotic processIEA:UniProtKB-KW
Cardiac muscle contractionIEA:Ensembl
Cardiac right ventricle morphogenesisIEA:Ensembl
Embryonic camera-type eye developmentIEA:Ensembl
Hair cycleIEA:Ensembl
Multicellular organism growthIEA:Ensembl
Multicellular organismal homeostasisIEA:Ensembl
Negative regulation of transcription by RNA polymerase IIIEA:Ensembl
Positive regulation of cell differentiationManual Assertion Based On ExperimentIBA:GO_Central
Post-embryonic developmentIEA:Ensembl
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Ventricular cardiac muscle tissue developmentIEA:Ensembl

Cellular Location

Cytoplasm
Nucleus
Predominantly cytoplasmic but also nuclear.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Related Products

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Recombinant Mouse Anti-PPP1R13L Recombinant Antibody (49.3) (CAT#: CBMAB-XB0954-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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