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Mouse Anti-PPP1R13L Recombinant Antibody (CBYY-I1479) (CBMAB-I2649-YY)

This product is Mouse antibody that recognizes PPP1R13L. The antibody CBYY-I1479 can be used for immunoassay techniques such as: WB, IP, IF, ELISA
See all PPP1R13L antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYY-I1479
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
PPP1R13L
Introduction
IASPP is one of the most evolutionarily conserved inhibitors of p53, whereas ASPP1 and ASPP2 (MIM 602143) are activators of p53.
Entrez Gene ID
10848
UniProt ID
Q8WUF5
Alternative Names
RAI; RAI4; IASPP; NKIP1
Function
Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis (PubMed:12524540).
Biological Process
Apoptotic processIEA:UniProtKB-KW
Cardiac muscle contractionIEA:Ensembl
Cardiac right ventricle morphogenesisIEA:Ensembl
Embryonic camera-type eye developmentIEA:Ensembl
Hair cycleIEA:Ensembl
Multicellular organism growthIEA:Ensembl
Multicellular organismal homeostasisIEA:Ensembl
Negative regulation of transcription by RNA polymerase IIIEA:Ensembl
Positive regulation of cell differentiationManual Assertion Based On ExperimentIBA:GO_Central
Post-embryonic developmentIEA:Ensembl
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Ventricular cardiac muscle tissue developmentIEA:Ensembl
Cellular Location
Cytoplasm
Nucleus
Predominantly cytoplasmic but also nuclear.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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