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Mouse Anti-PRKAR2A Recombinant Antibody (1A7) (CBMAB-P2812-YC)

Provided herein is a Mouse monoclonal antibody against Human Protein Kinase CAMP-Dependent Type II Regulatory Subunit Alpha. The antibody can be used for immunoassay techniques, such as FC, IF, IHC, WB.
See all PRKAR2A antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1A7
Antibody Isotype
IgG1
Application
FC, IF, IHC, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
protein kinase cAMP-dependent type II regulatory subunit alpha
Introduction
PRKAR2A (Protein Kinase CAMP-Dependent Type II Regulatory Subunit Alpha) is a protein coding gene. Diseases associated with PRKAR2A include Kallmann Syndrome. Among its related pathways are Melanocyte Development and Pigmentation and G-protein signaling G-Protein alpha-i signaling cascades. Gene Ontology annotations related to this gene include ubiquitin protein ligase binding and cAMP binding.
Entrez Gene ID
5576
UniProt ID
P13861
Alternative Names
PKR2; PRKAR2
Function
Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.
Biological Process
Intracellular signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Negative regulation of cAMP-dependent protein kinase activityManual Assertion Based On ExperimentIDA:BHF-UCL
Cellular Location
Cytoplasm
Cell membrane
Colocalizes with PJA2 in the cytoplasm and the cell membrane.
PTM
Phosphorylated by the activated catalytic chain.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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