Mouse Anti-PROK1 Recombinant Antibody (2L13) (CBMAB-P2981-YC)

Name: Mouse Anti-PROK1 Recombinant Antibody (2L13)
SKU: CBMAB-P2981-YC
Rating: 5 (1 reviews)

See all PROK1 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

2L13

Application

WB, ELISA, IHC-P

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG2

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

prokineticin 1

Introduction

PROK1 induces proliferation, migration, and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. It has little or no effect on a variety of other endothelial and non-endothelial cell types. Its expression is restricted to the steroidogenic glands (ovary, testis, adrenal, and placenta), is induced by hypoxia, and often complementary to the expression of vascular endothelial growth factor (VEGF), suggesting that these molecules function in a coordinated manner.

Entrez Gene ID

Human	84432
Mouse	246691
Rat	192205

UniProt ID

Human	P58294
Mouse	Q14A28
Rat	Q8R414

Alternative Names

EG-VEGF

Function

Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis.

Biological Process

AngiogenesisIEA:UniProtKB-KW
Positive regulation of cell divisionIEA:UniProtKB-KW
Positive regulation of MAPK cascadeIEA:Ensembl
Positive regulation of vascular endothelial cell proliferationIEA:Ensembl
Regulation of angiogenesisIEA:Ensembl
Vascular endothelial cell proliferationIEA:Ensembl

Cellular Location

Secreted

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-PROK1 Recombinant Antibody (2L13)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-PROK1 Recombinant Antibody (3C3) (CAT#: CBMAB-A7079-LY)

Mouse Anti-PROK1 Recombinant Antibody (CBYC-P651) (CAT#: CBMAB-P2983-YC)

Mouse Anti-PROK1 Recombinant Antibody (CBFYE-1609) (CAT#: CBMAB-E2268-FY)

Rabbit Anti-PROK1 Recombinant Antibody (CBYC-P650) (CAT#: CBMAB-P2982-YC)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry