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Mouse Anti-PROK1 Recombinant Antibody (CBFYE-1609) (CBMAB-E2268-FY)

This product is mouse antibody that recognizes PROK1. The antibody CBFYE-1609 can be used for immunoassay techniques such as: ELISA, IHC, WB.
See all PROK1 antibodies
Published Data

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBFYE-1609
Antibody Isotype
IgG2
Application
ELISA, IHC, WB

Basic Information

Immunogen
Recombinant protein corresponding to human EG-VEGF
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG2
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
PBS
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
prokineticin 1
Introduction
The protein encoded by this gene induces proliferation, migration, and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. It has little or no effect on a variety of other endothelial and non-endothelial cell types.
Entrez Gene ID
Human84432
Mouse246691
Rat192205
UniProt ID
HumanP58294
MouseQ14A28
RatQ8R414
Alternative Names
PK1; PRK1; EGVEGF
Function
Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis.
Biological Process
AngiogenesisIEA:UniProtKB-KW
Positive regulation of cell divisionIEA:UniProtKB-KW
Positive regulation of MAPK cascadeIEA:Ensembl
Positive regulation of vascular endothelial cell proliferationIEA:Ensembl
Regulation of angiogenesisIEA:Ensembl
Vascular endothelial cell proliferationIEA:Ensembl
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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