Sign in or Register   Sign in or Register
  |  

Mouse Anti-PROK1 Recombinant Antibody (3C3) (CBMAB-A7079-LY)

The product is antibody recognizes PROK1. The antibody 3C3 immunoassay techniques such as: sELISA, ELISA.
See all PROK1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3C3
Antibody Isotype
IgG2b, κ
Application
sELISA, ELISA

Basic Information

Immunogen
PROK1 (AAH25399, 1 a.a. ~ 105 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
prokineticin 1
Introduction
Endocrine gland-derived vascular endothelial growth factor (EG-VEGF) induces proliferation, migration, and fenestration in capillary endothelial cells derived from endocrine glands. Its expression is induced by hypoxia and is restricted to the steroidogenic glands (ovary, testis, adrenal, and placenta). Its expression is often complementary to the expression of VEGF (MIM 192240), suggesting that these molecules function in a coordinated manner.[supplied by OMIM
Entrez Gene ID
84432
UniProt ID
P58294
Alternative Names
EGVEGF; PK1; PRK1
Function
Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis.
Biological Process
AngiogenesisIEA:UniProtKB-KW
Positive regulation of cell divisionIEA:UniProtKB-KW
Positive regulation of MAPK cascadeIEA:Ensembl
Positive regulation of vascular endothelial cell proliferationIEA:Ensembl
Regulation of angiogenesisIEA:Ensembl
Vascular endothelial cell proliferationIEA:Ensembl
Cellular Location
Secreted
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-PROK1 Recombinant Antibody (3C3)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare