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Mouse Anti-SEPT10 Recombinant Antibody (3A9) (CBMAB-A7978-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
3A9
Antibody Isotype
IgG2b, κ
Application
WB, ELISA

Basic Information

Immunogen
SEPT10 (AAH20502, 1 a.a. ~ 454 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
septin 10
Introduction
This gene encodes a member of the septin family of cytoskeletal proteins with GTPase activity. This protein localizes to the cytoplasm and nucleus and displays GTP-binding and GTPase activity. Alternate splicing results in two transcript variants encoding different isoforms. [provided by RefSeq]
Entrez Gene ID
151011
UniProt ID
Q9P0V9
Alternative Names
FLJ11619
Function
Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential).
Biological Process
Biological Process cytoskeleton-dependent cytokinesisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process protein localizationManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm
Cytoplasm, cytoskeleton
Cell projection, cilium, flagellum
Detected in the annulus of the sperm flagellum and in the neck region in spermatids and mature sperm (By similarity).
Using a GFP-fusion protein, detected in the nucleus.
PTM
Proteolytically cleaved in vitro in a calmodulin-dependent manner.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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