Mouse Anti-SEPT10 Recombinant Antibody (CBXS-4340) (CBMAB-S1585-CQ)

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Basic Information

Host Animal
Mouse
Clone
CBXS-4340
Application
ELISA, ICC, IF, WB
Immunogen
SEPT10 (AAH20502, 1 a.a.-454 a.a) Full length recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
septin 10
Introduction
This gene encodes a member of the septin family of cytoskeletal proteins with GTPase activity. This protein localizes to the cytoplasm and nucleus and displays GTP-binding and GTPase activity. A pseudogene for this gene is located on chromosome 8. Alternative splicing results in multiple transcript variants.
Entrez Gene ID
UniProt ID
Alternative Names
Septin 10; Sept1-Like; Septin-10;
Function
Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential).
Biological Process
Biological Process cytoskeleton-dependent cytokinesisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process protein localizationManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm
Cytoplasm, cytoskeleton
Cell projection, cilium, flagellum
Detected in the annulus of the sperm flagellum and in the neck region in spermatids and mature sperm (By similarity).
Using a GFP-fusion protein, detected in the nucleus.
PTM
Proteolytically cleaved in vitro in a calmodulin-dependent manner.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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