SEPT10
This gene encodes a member of the septin family of cytoskeletal proteins with GTPase activity. This protein localizes to the cytoplasm and nucleus and displays GTP-binding and GTPase activity. Alternate splicing results in two transcript variants encoding different isoforms. [provided by RefSeq]
Full Name
septin 10
Function
Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential).
Biological Process
Biological Process cytoskeleton-dependent cytokinesisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process protein localizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process protein localizationManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm
Cytoplasm, cytoskeleton
Cell projection, cilium, flagellum
Detected in the annulus of the sperm flagellum and in the neck region in spermatids and mature sperm (By similarity).
Using a GFP-fusion protein, detected in the nucleus.
Cytoplasm, cytoskeleton
Cell projection, cilium, flagellum
Detected in the annulus of the sperm flagellum and in the neck region in spermatids and mature sperm (By similarity).
Using a GFP-fusion protein, detected in the nucleus.
PTM
Proteolytically cleaved in vitro in a calmodulin-dependent manner.
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Anti-SEPT10 antibodies
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Target: SEPT10
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 3A9
Application*: WB, E
Target: SEPT10
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2A12
Application*: WB, E
Target: SEPT10
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBCNC-701
Application*: WB
Target: SEPT10
Host: Mouse
Specificity: Human
Clone: CBXS-3010
Application*: E, WB
Target: SEPT10
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXS-4340
Application*: E, IC, IF, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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