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Mouse Anti-SEPT10 Recombinant Antibody (CBCNC-701) (CBMAB-C4269-CN)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBCNC-701
Antibody Isotype
IgG1
Application
WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
septin 10
Introduction
This gene encodes a member of the septin family of cytoskeletal proteins with GTPase activity. This protein localizes to the cytoplasm and nucleus and displays GTP-binding and GTPase activity. A pseudogene for this gene is located on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012]
Entrez Gene ID
151011
UniProt ID
Q9P0V9
Alternative Names
Septin 10; Sept1-Like; Septin-10;
Function
Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential).
Biological Process
Biological Process cytoskeleton-dependent cytokinesisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process protein localizationManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm
Cytoplasm, cytoskeleton
Cell projection, cilium, flagellum
Detected in the annulus of the sperm flagellum and in the neck region in spermatids and mature sperm (By similarity).
Using a GFP-fusion protein, detected in the nucleus.
PTM
Proteolytically cleaved in vitro in a calmodulin-dependent manner.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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