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Mouse Anti-SSR1 Recombinant Antibody (CBXS-3797) (CBMAB-S1068-CQ)

This product is a mouse antibody that recognizes SSR1. The antibody CBXS-3797 can be used for immunoassay techniques such as: ELISA, WB, IHC-P.
See all SSR1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-3797
Antibody Isotype
IgG1, κ
Application
ELISA, WB, IHC-P

Basic Information

Immunogen
Recombinant protein
Specificity
Human
Antibody Isotype
IgG1, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
signal sequence receptor, alpha
Introduction
The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are mostly non-canonical. Multiple transcript variants encoding different isoforms have been found for this gene.
Entrez Gene ID
UniProt ID
Alternative Names
Signal Sequence Receptor Subunit 1; Signal Sequence Receptor Subunit Alpha; Signal Sequence Receptor, Alpha; SSR-Alpha; TRAPA; Translocon-Associated Protein Alpha Subunit;
Function
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.
Biological Process
Biological Process cotranslational protein targeting to membraneManual Assertion Based On ExperimentTAS:ProtInc
Biological Process positive regulation of cell population proliferationManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Endoplasmic reticulum membrane
Topology
Lumenal: 19-207
Helical: 208-228
Cytoplasmic: 229-286
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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