Mouse Anti-SSR1 Recombinant Antibody (CBXS-0735) (CBMAB-S3666-CQ)

Name: Mouse Anti-SSR1 Recombinant Antibody (CBXS-0735)
SKU: CBMAB-S3666-CQ
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBXS-0735

Application

S-ELISA, ELISA, WB, IHC-P

Immunogen

SSR1 (AAH07710, 33 a.a.-286 a.a) Full length recombinant protein with GST tag

Specificity

Human

Antibody Isotype

IgG1, κ

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

signal sequence receptor, alpha

Introduction

The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are mostly non-canonical. Multiple transcript variants encoding different isoforms have been found for this gene.

Entrez Gene ID

6745

UniProt ID

P43307

Alternative Names

Signal Sequence Receptor Subunit 1; Signal Sequence Receptor Subunit Alpha; Signal Sequence Receptor, Alpha; SSR-Alpha; TRAPA; Translocon-Associated Protein Alpha Subunit;

Function

TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.

Biological Process

Biological Process cotranslational protein targeting to membraneManual Assertion Based On ExperimentTAS:ProtInc
Biological Process positive regulation of cell population proliferationManual Assertion Based On ExperimentTAS:ProtInc

Cellular Location

Endoplasmic reticulum membrane

Topology

Lumenal: 19-207
Helical: 208-228
Cytoplasmic: 229-286

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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