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SSR1

The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are mostly non-canonical. [provided by RefSeq]
Full Name
signal sequence receptor, alpha
Function
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.
Biological Process
Biological Process cotranslational protein targeting to membraneManual Assertion Based On ExperimentTAS:ProtInc
Biological Process positive regulation of cell population proliferationManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Endoplasmic reticulum membrane
Topology
Lumenal: 19-207
Helical: 208-228
Cytoplasmic: 229-286
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Anti-SSR1 antibodies

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Mouse Anti-SSR1 Recombinant Antibody (1C11) (CBMAB-A8612-LY)

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Target: SSR1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1C11
Application*: WB, E
Datasheet SDS

Mouse Anti-SSR1 Recombinant Antibody (1A12) (CBMAB-A8611-LY)

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Target: SSR1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1A12
Application*: WB, E
Datasheet SDS

Mouse Anti-SSR1 Recombinant Antibody (CBYJT-1688) (CBMAB-T0738-YJ)

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Target: SSR1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Monkey
Clone: CBYJT-1688
Application*: WB, F, IH, IC, IF, P
Datasheet SDS

Mouse Anti-SSR1 Recombinant Antibody (CBYJT-1687) (CBMAB-T0737-YJ)

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Target: SSR1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-1687
Application*: WB, P
Datasheet SDS

Mouse Anti-SSR1 Recombinant Antibody (CBXS-0735) (CBMAB-S3666-CQ)

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Target: SSR1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXS-0735
Application*: SE, E, WB, P
Datasheet SDS

Mouse Anti-SSR1 Recombinant Antibody (CBXS-5010) (CBMAB-S2232-CQ)

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Target: SSR1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5010
Application*: F, WB
Datasheet SDS

Mouse Anti-SSR1 Recombinant Antibody (CBXS-4868) (CBMAB-S2091-CQ)

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Target: SSR1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4868
Application*: F, IF, P, WB
Datasheet SDS

Mouse Anti-SSR1 Recombinant Antibody (CBXS-3852) (CBMAB-S1122-CQ)

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Target: SSR1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-3852
Application*: F, WB
Datasheet SDS

Mouse Anti-SSR1 Recombinant Antibody (CBXS-3797) (CBMAB-S1068-CQ)

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Target: SSR1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXS-3797
Application*: E, WB, P
Datasheet SDS

Mouse Anti-SSR1 Recombinant Antibody (CBXS-5680) (CBMAB-S0550-CQ)

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Target: SSR1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5680
Application*: F, IF, P, WB
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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