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Mouse Anti-TCL1A Recombinant Antibody (CBYJT-2308) (CBMAB-T1418-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TCL1A (T Cell Leukemia/Lymphoma 1A). The antibody can be used for immunoassay techniques, such as ELISA, WB, IHC-P, IF, ICC, FC.
Host Animal
Mouse
Application
ELISA, WB, IHC-P, IF, ICC, FC
Immunogen
Human TCL1A expressed in E. coli
Antibody Isotype
IgG1
Specificity
Human
Cross Reactivity
Human
Clone
CBYJT-2308
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Introduction
TCL1A is a subunit of TCL1. Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 plays a role as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).
Alternative Name
T Cell Leukemia/Lymphoma 1A; T-Cell Leukemia/Lymphoma 1A; Protein P14 TCL1; Oncogene TCL-1; Oncogene TCL1; TCL1; T-Cell Leukemia/Lymphoma Protein 1A; T-Cell Lymphoma-1
Entrez Gene ID
UniProt ID