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Mouse Anti-TMOD1 Recombinant Antibody (TRM-17 (Mab17)) (CBMAB-T2863-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to TMOD1 (Tropomodulin 1). The antibody can be used for immunoassay techniques, such as ELISA, IF, WB.
See all TMOD1 antibodies

Summary

Host Animal
Mouse
Specificity
Chicken
Clone
TRM-17 (Mab17)
Antibody Isotype
IgG1
Application
ELISA, IF, WB

Basic Information

Immunogen
Recombinant chicken E-Tmod located at N-terminal
Specificity
Chicken
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS
Preservative
0.05% Sodium Azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
N-terminus

Target

Full Name
TMOD1 Gene(Protein Coding) Tropomodulin 1
Introduction
TMOD1 functions in pointed-end actin filament capping.
Entrez Gene ID
UniProt ID
Alternative Names
E-Tmod; tropomodulin-1
Function
Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus.
Biological Process
Biological Process actin filament organizationSource:GO_Central1 Publication
Biological Process adult locomotory behaviorSource:Ensembl
Biological Process lens fiber cell developmentSource:Ensembl
Biological Process muscle contractionSource:GO_Central1 Publication
Biological Process myofibril assemblySource:GO_Central1 Publication
Biological Process pointed-end actin filament cappingSource:InterPro
Cellular Location
Cytoplasm, cytoskeleton
In myofibrils with sarcomeric structure, localizes to the pointed end of actin thin filaments (PubMed:25250574).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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