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Mouse Anti-TNFRSF17 Recombinant Antibody (CBT4648) (V2LY-0625-LY783)


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Tested Data
Mouse Anti-TNFRSF17 Recombinant Antibody (CBT4648) (V2LY-0625-LY783) in ELISA
Mouse Anti-TNFRSF17 Recombinant Antibody (CBT4648) (V2LY-0625-LY783) in ELISA
Mouse Anti-TNFRSF17 Recombinant Antibody (CBT4648) (V2LY-0625-LY783) in WB
Mouse Anti-TNFRSF17 Recombinant Antibody (CBT4648) (V2LY-0625-LY783) in WB
Mouse Anti-TNFRSF17 Recombinant Antibody (CBT4648) (V2LY-0625-LY783) in FC
Mouse Anti-TNFRSF17 Recombinant Antibody (CBT4648) (V2LY-0625-LY783) in FC

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBT4648
Antibody Isotype
IgG1
Application
FC

Basic Information

Immunogen
Purified recombinant fragment of human BCMA (AA: QMAGQCSQNEYFDSLc) expressed in E. Coli.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:500-1:2,000
FC1:200-1:400
ELISA1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
Sodium azide
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
TNFRSF17 Gene(Protein Coding) TNF Receptor Superfamily Member 17
Entrez Gene ID
608
Function
Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
Biological Process
Biological Process adaptive immune response Source:UniProtKB-KW
Biological Process lymphocyte homeostasis Source:Ensembl
Biological Process signal transduction Source:ProtInc1 Publication
Biological Process tumor necrosis factor-mediated signaling pathway Source:InterPro
Cellular Location
Cell membrane
Endomembrane system
Involvement in disease
A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2.
Topology
Extracellular: 1-54
Helical: 55-77
Cytoplasmic: 78-184
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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