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Armenian Hamster Anti-TNFSF13 Recombinant Antibody (CBWJC-4548) (CBMAB-C5944WJ)

This product is a Armenian Hamster antibody that recognizes TNFSF13. This antibody CBWJC-4548 can be used for immunoassay techniques such as: ICFC, ELISA.
See all TNFSF13 antibodies

Summary

Host Animal
Armenian Hamster
Specificity
Mouse
Clone
CBWJC-4548
Antibody Isotype
IgG
Application
ICFC, ELISA

Basic Information

Immunogen
Fusion protein of murine Maltose binding protein (MBP) and soluble April
Specificity
Mouse
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Preservative
0.09% sodium azide
Concentration
0.5 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
tumor necrosis factor (ligand) superfamily, member 13
Introduction
The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010]
Entrez Gene ID
69583
UniProt ID
Q9D777
Alternative Names
TNF Superfamily Member 13; Tumor Necrosis Factor (Ligand) Superfamily, Member 13; TNF- And APOL-Related Leukocyte Expressed Ligand 2; A Proliferation-Inducing Ligand; TALL-2; TRDL-1; APRIL; TALL2; ZTNF2; Tumor Necrosis Factor Ligand Superfamily Member 13;
Function
Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes.
Biological Process
Biological Process immune response Source:InterPro
Biological Process positive regulation of cell population proliferation Source:ProtInc1 Publication
Biological Process positive regulation of isotype switching to IgA isotypes Source:MGI1 Publication
Biological Process signal transduction Source:ProtInc1 Publication
Cellular Location
Secreted
PTM
The precursor is cleaved by furin.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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