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Rat Anti-TNFSF13 Recombinant Antibody (CBYJT-3933) (CBMAB-T3340-YJ)

Provided herein is a Rat monoclonal antibody, which binds to TNFSF13 (TNF Superfamily Member 13). The antibody can be used for immunoassay techniques, such as ICC, FC.
See all TNFSF13 antibodies

Summary

Host Animal
Rat
Specificity
Human, Mouse
Clone
CBYJT-3933
Antibody Isotype
IgG2a
Application
ICC, FC

Basic Information

Immunogen
APRIL (monoclonal Sache-1) antibody was raised against recombinant human APRIL (aa. 105-250)
Specificity
Human, Mouse
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS
Preservative
0.02% Sodium Azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 105-250

Target

Full Name
tumor necrosis factor (ligand) superfamily, member 13
Introduction
TNFSF13 is a member of the tumor necrosis factor (TNF) ligand family. It is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. TNFSF13 and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM.
Entrez Gene ID
Human8741
Mouse69583
UniProt ID
HumanO75888
MouseQ9D777
Alternative Names
TNF Superfamily Member 13; Tumor Necrosis Factor (Ligand) Superfamily, Member 13; TNF- And APOL-Related Leukocyte Expressed Ligand 2; A Proliferation-Inducing Ligand; TALL-2; TRDL-1; APRIL; TALL2; ZTNF2; Tumor Necrosis Factor Ligand Superfamily Member 13
Function
Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes.
Biological Process
Biological Process immune response Source:InterPro
Biological Process positive regulation of cell population proliferation Source:ProtInc1 Publication
Biological Process positive regulation of isotype switching to IgA isotypes Source:MGI1 Publication
Biological Process signal transduction Source:ProtInc1 Publication
Cellular Location
Secreted
PTM
The precursor is cleaved by furin.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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