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Rat Anti-TNFSF9 Recombinant Antibody (AG185) (V2LY-0524-LY81)

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Summary

Host Animal
Rat
Specificity
Mouse
Clone
AG185
Antibody Isotype
IgG2a, κ
Application
FC, In Vivo

Basic Information

Immunogen
BALB/c mouse B lymphoma line 2PK-3
Host Species
Rat
Specificity
Mouse
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal Antibody

Formulations & Storage [For reference only, actual COA shall prevail!]

Endotoxin
< 1.0 EU/mg as determined by the LAL method
Format
Liquid
Buffer
PBS
Preservative
None
Concentration
5 mg/ml
Purity
>95% by SDS Page
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
TNFSF9 Gene(Protein Coding) TNF Superfamily Member 9
Entrez Gene ID
UniProt ID
Alternative Names
TNF Superfamily Member 9; Tumor Necrosis Factor (Ligand) Superfamily, Member 9; Homolog Of Mouse 4-1BB-L; Receptor 4-1BB Ligand; 4-1BB Ligand; 4-1BBL; Tumor Necrosis Factor Ligand Superfamily Member 9;
Function
Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.
Biological Process
Biological Process cell-cell signaling Source:ProtInc1 Publication
Biological Process immune response Source:InterPro
Biological Process positive regulation of activated T cell proliferation Source:GO_Central1 Publication
Biological Process positive regulation of cytotoxic T cell differentiation Source:GO_Central1 Publication
Biological Process regulation of apoptotic process Source:GO_Central1 Publication
Biological Process regulation of T cell proliferation Source:GO_Central1 Publication
Cellular Location
Membrane
Topology
Cytoplasmic: 1-28
Helical: 29-49
Extracellular: 50-254
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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