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Mouse Anti-TNNT3 Recombinant Antibody (CBYJT-4109) (CBMAB-T3548-YJ)

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Basic Information

Host Animal
Mouse
Clone
CBYJT-4109
Application
WB, ELISA
Immunogen
Purified chicken breast muscle
Specificity
Chicken, Mouse, Rat, Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
TNNT3
Introduction
TNNT3 functions in processes such as regulation of ATPase activity, regulation of striated muscle contraction, skeletal muscle contraction.
Entrez Gene ID
Human7140
Mouse21957
Rat24838
Chicken395761
UniProt ID
HumanP45378
MouseQ9QZ47
RatP09739
ChickenP12620
Function
Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Biological Process
Biological Process muscle contraction Source:GO_Central1 Publication
Biological Process positive regulation of calcium-dependent ATPase activity Source:UniProtKB2 Publications
Biological Process regulation of ATP-dependent activity Source:UniProtKB1 Publication
Biological Process regulation of striated muscle contraction Source:UniProtKB1 Publication
Biological Process sarcomere organization Source:GO_Central1 Publication
Biological Process skeletal muscle contraction Source:UniProtKB1 Publication
Cellular Location
cytosol
troponin complex
Involvement in disease
rthrogryposis, distal, 2B2 (DA2B2):
A form of distal arthrogryposis, a disease characterized by congenital joint contractures that mainly involve two or more distal parts of the limbs, in the absence of a primary neurological or muscle disease. Distal arthrogryposis type 2 is characterized by contractures of the hands and feet, and a distinctive face characterized by prominent nasolabial folds, small mouth and downslanting palpebral fissures. DA2B2 inheritance is autosomal dominant.
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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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