Sign in or Register   Sign in or Register
  |  

Mouse Anti-TOE1 Recombinant Antibody (1C12) (CBMAB-A9417-LY)

The product is antibody recognizes TOE1. The antibody 1C12 immunoassay techniques such as: WB, ELISA.
See all TOE1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1C12
Antibody Isotype
IgG1, κ
Application
WB, ELISA

Basic Information

Immunogen
TOE1 (AAH09364, 1 a.a. ~ 510 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
TOE1 Gene(Protein Coding) Target Of EGR1, Exonuclease
Entrez Gene ID
114034
UniProt ID
Q96GM8
Alternative Names
FLJ13949
Function
Inhibits cell growth rate and cell cycle. Induces CDKN1A expression as well as TGF-beta expression. Mediates the inhibitory growth effect of EGR1. Involved in the maturation of snRNAs and snRNA 3'-tail processing (PubMed:28092684).
Biological Process
Biological Process RNA phosphodiester bond hydrolysis, exonucleolytic Source:HGNC1 Publication
Biological Process snRNA 3'-end processing Source:UniProtKB1 Publication
Cellular Location
Nucleus, nucleolus
Nucleus speckle
Localizes to nuclear speckles.
Involvement in disease
Pontocerebellar hypoplasia 7 (PCH7):
A form of pontocerebellar hypoplasia, a group of related disorders characterized by underdevelopment of the pons and the cerebellum. Pontocerebellar hypoplasia also causes impaired growth of other parts of the brain, leading to an unusually small head size. PCH7 patients manifest delayed psychomotor development, hypotonia, breathing abnormalities, and gonadal abnormalities.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-TOE1 Recombinant Antibody (1C12)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare