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Rat Anti-Treml1 Recombinant Antibody (CBYJT-4622) (CBMAB-T4151-YJ)

Provided herein is a Rat monoclonal antibody, which binds to Treml1 (Triggering Receptor Expressed On Myeloid Cells-Like 1). The antibody can be used for immunoassay techniques, such as WB.
See all Treml1 antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBYJT-4622
Antibody Isotype
IgG2b
Application
WB

Basic Information

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse TREML1/TLT-1, Gly18-Cys178, Accession # NP_082039
Specificity
Mouse
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, Trehalose
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 18-178

Target

Full Name
Triggering Receptor Expressed On Myeloid Cells-Like 1
Introduction
Treml1 is a cell surface receptor that may function in the innate and adaptive immune response.
Entrez Gene ID
71326
UniProt ID
Q8K558
Alternative Names
TLT-1; 5430401J17Rik
Function
Cell surface receptor that may play a role in the innate and adaptive immune response.
Biological Process
Biological Process calcium-mediated signaling Source:UniProtKB
Biological Process innate immune response Source:UniProtKB1 Publication
Biological Process platelet activation Source:UniProtKB1 Publication
Cellular Location
Cell membrane
Cytoplasm
Sequestered in cytoplasmic vesicles in resting platelets (PubMed:15100151).
Transported to the cell surface after stimulation by thrombin (PubMed:15100151).
Soluble fragments can be released into the serum by proteolysis (PubMed:16505478).
Topology
Extracellular: 16-162
Helical: 163-183
Cytoplasmic: 184-311
PTM
Phosphorylated on tyrosine residues.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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